WormBase Tree Display for Gene: WBGene00012448
expand all nodes | collapse all nodes | view schema
WBGene00012448 | SMap | S_parent | Sequence | CHROMOSOME_V | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cyp | ||||||
Allele (116) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Ortholog (114) | |||||||
Paralog (44) | |||||||
Structured_description | Automated_description | Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Keshan disease; glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C8 (cytochrome P450 family 2 subfamily C member 8). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (46) | ||||||
Molecular_info | Corresponding_CDS | Y17D7A.4 | |||||
Corresponding_CDS_history | Y17D7A.4:wp106 | ||||||
Corresponding_transcript | Y17D7A.4.1 | ||||||
Other_sequence (20) | |||||||
Associated_feature | WBsf982076 | ||||||
WBsf1003019 | |||||||
WBsf1021557 | |||||||
Experimental_info | RNAi_result | WBRNAi00036657 | Inferred_automatically | RNAi_primary | |||
WBRNAi00092667 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00055560 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00095077 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1021931 | ||||||
Expr1159061 | |||||||
Expr2010722 | |||||||
Expr2028960 | |||||||
Microarray_results (15) | |||||||
Expression_cluster (106) | |||||||
Interaction (35) | |||||||
Map_info | Map | V | Position | 18.0657 | Error | 0.02692 | |
Positive | Positive_clone | Y17D7A | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00038491 | ||||||
WBPaper00055090 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |