WormBase Tree Display for Gene: WBGene00012184

WBGene00012184 SMap: S_parent: Sequence: W01F3
  Identity: Version: 2
    Name: CGC_name: mnr-1 Paper_evidence: WBPaper00044291
            WBPaper00044290
          Person_evidence: WBPerson1705
      Sequence_name: W01F3.1
      Molecular_name: W01F3.1a
        W01F3.1a.1
        CE26981
        W01F3.1b
        CE26982
        W01F3.1b.1
      Other_name: CELE_W01F3.1 Accession_evidence: NDB BX284605
      Public_name: mnr-1
    DB_info: Database: AceView gene 5V129
        WormQTL gene WBGene00012184
        WormFlux gene WBGene00012184
        NDB locus_tag CELE_W01F3.1
        Panther gene CAEEL|WormBase=WBGene00012184|UniProtKB=O45879
          family PTHR21184
        NCBI gene 180350
        RefSeq protein NM_075589.8
            NM_075590.6
        TREEFAM TREEFAM_ID TF315079
        TrEMBL UniProtAcc Q9BI60
            O45879
        UniProt_GCRP UniProtAcc O45879
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 16 Sep 2013 09:36:57 WBPerson2970 Name_change: CGC_name: mnr-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mnr
    Allele (133)
    Strain: WBStrain00002811
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (37)
    Structured_description: Automated_description: Involved in neuron development and regulation of cell morphogenesis. Located in extracellular space and plasma membrane. Expressed in ALA; pharynx; and tail neurons. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Is an ortholog of human FAM151B (family with sequence similarity 151 member B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0050861 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:25032)
  Molecular_info: Corresponding_CDS: W01F3.1a
      W01F3.1b
    Corresponding_CDS_history: W01F3.1a:wp46
      W01F3.1b:wp46
    Corresponding_transcript: W01F3.1a.1
      W01F3.1b.1
    Other_sequence: CRC03850_1
      CR08364
      JI169026.1
      CR01176
      Dviv_isotig32906
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00019469 Inferred_automatically: RNAi_primary
      WBRNAi00113582 Inferred_automatically: RNAi_primary
      WBRNAi00054528 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1213
      Chronogram1719
      Expr6811
      Expr11330
      Expr11333
      Expr14554
      Expr1026298
      Expr1158074
      Expr2013633
      Expr2031867
    Drives_construct: WBCnstr00003338
      WBCnstr00018438
      WBCnstr00030078
      WBCnstr00041158
    Construct_product: WBCnstr00018395
      WBCnstr00018431
      WBCnstr00018432
      WBCnstr00018433
      WBCnstr00018437
      WBCnstr00018438
      WBCnstr00030078
      WBCnstr00041158
    Microarray_results (30)
    Expression_cluster: WBPaper00030922:glycosylated_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Spermatogenic
      WBPaper00046121:ecdoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00051311:VGLN-1-interacting
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AIB
      WBPaper00061340:AIM
      WBPaper00061340:ASG_AWA
      WBPaper00061340:ASK_parent
      WBPaper00061340:AVD
      WBPaper00061340:AVE
      WBPaper00061340:AVG
      WBPaper00061340:AVK
      WBPaper00061340:DA_DB
      WBPaper00061340:Excretory_duct_and_pore
      WBPaper00061340:F_U
      WBPaper00061340:ILsh_OLLsh_OLQsh
      WBPaper00061340:K_Kprime
      WBPaper00061340:Neuroblast_I6_M5
      WBPaper00061340:Parent_of_exc_duct_pore_DB_1_3
      WBPaper00061340:Parent_of_exc_gland_AVK
      WBPaper00061340:Parent_of_MI_pm1DR
      WBPaper00061340:Parent_of_PVP_and_rect_V
      WBPaper00061340:pm6
      WBPaper00061340:rect_D
      WBPaper00061340:RIC_parent
      WBPaper00061340:RID
      WBPaper00061340:RIH
      WBPaper00061340:RIM_parent
      WBPaper00061340:RIS
      WBPaper00061340:RIV
      WBPaper00061340:SIB
      WBPaper00061340:T
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:mup-2-unc-87_284
      WBPaper00061651:ALA_enriched
      WBPaper00061651:AVA_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:46_0
      WBPaper00065841:61_0
      WBPaper00065841:139_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_4_4
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00027111:eri-1(mg366)_downregulated
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032948:FedUp
      WBPaper00035873:dpy-9_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00037695:LD_3-day
      WBPaper00037695:WC_5-day
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040426:CYE-1_CDK-2AF_upregulated
      WBPaper00040821:Au-NP_regulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040963:TA300_up
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00042234:xpa-1_upregulated
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(186_min)
      [cgc5767]:expression_class_SE
      [cgc5767]:expression_class_SE_pi(186_min)
    Interaction: WBInteraction000434264
      WBInteraction000503267
      WBInteraction000542998
      WBInteraction000542999
      WBInteraction000543027
      WBInteraction000555492
      WBInteraction000556215
      WBInteraction000556221
  Map_info: Map: V Position: 25.0304
    Positive: Positive_clone: W01F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene