WormBase Tree Display for Gene: WBGene00012156
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WBGene00012156 | SMap | S_parent | Sequence | VW02B12L | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | ebp-2 | Person_evidence | WBPerson1480 | |||||
Sequence_name | VW02B12L.3 | ||||||||
Molecular_name | VW02B12L.3 | ||||||||
VW02B12L.3.1 | |||||||||
CE18982 | |||||||||
Other_name | CELE_VW02B12L.3 | Accession_evidence | NDB | BX284602 | |||||
Public_name | ebp-2 | ||||||||
DB_info | Database | AceView | gene | 2L733 | |||||
WormQTL | gene | WBGene00012156 | |||||||
WormFlux | gene | WBGene00012156 | |||||||
NDB | locus_tag | CELE_VW02B12L.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00012156|UniProtKB=Q9XXA2 | |||||||
family | PTHR10623 | ||||||||
NCBI | gene | 174744 | |||||||
RefSeq | protein | NM_064037.7 | |||||||
TREEFAM | TREEFAM_ID | TF313620 | |||||||
TrEMBL | UniProtAcc | Q9XXA2 | |||||||
UniProt_GCRP | UniProtAcc | Q9XXA2 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 09 Jun 2005 10:01:00 | WBPerson2970 | Name_change | CGC_name | ebp-2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ebp | ||||||||
Allele (22) | |||||||||
Strain | WBStrain00036705 | ||||||||
WBStrain00036737 | |||||||||
WBStrain00034624 | |||||||||
WBStrain00007423 | |||||||||
WBStrain00053560 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (18) | |||||||||
Contained_in_operon | CEOP2536 | ||||||||
Ortholog (49) | |||||||||
Paralog | WBGene00007062 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00013344 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | ebp-2 encodes an RP/EB-type microtubule-binding protein orthologous to human MAPRE1 (OMIM:603108), MAPRE2 (OMIM:605789), MAPRE3 (OMIM:605788), and paralogous to EBP-1/-3; EBP-2 binds the plus ends of growing microtubules; by orthology, the N-terminal calponin homology domain of EBP-2 is predicted to bind microtubules (MTs), while the C-terminal region of EBP-2 is predicted to contain a dimerization domain and a site for binding protein ligands that activate EBP-2's MT-binding; ebp-2(RNAi) animals have no obvious phenotypes, perhaps because of genetic redundancy with ebp-1 and ebp-3. | Paper_evidence | WBPaper00026660 | |||||
WBPaper00031417 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 25 Jan 2014 00:00:00 | ||||||||
Automated_description | Predicted to enable microtubule plus-end binding activity. Predicted to be involved in protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and non-motile cilium. Expressed in several structures, including hypodermis; nervous system; and ventral nerve cord. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | VW02B12L.3 | |||||||
Corresponding_transcript | VW02B12L.3.1 | ||||||||
Other_sequence (12) | |||||||||
Associated_feature | WBsf644680 | ||||||||
WBsf222136 | |||||||||
WBsf222137 | |||||||||
WBsf222138 | |||||||||
Experimental_info | RNAi_result | WBRNAi00054475 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00036123 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00019437 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00062390 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr3660 | ||||||||
Expr3661 | |||||||||
Expr13607 | |||||||||
Expr16485 | |||||||||
Expr1023670 | |||||||||
Expr1035377 | |||||||||
Expr1158021 | |||||||||
Expr2011163 | |||||||||
Expr2029399 | |||||||||
Construct_product (12) | |||||||||
Antibody | WBAntibody00000867 | ||||||||
Microarray_results (20) | |||||||||
Expression_cluster (125) | |||||||||
Interaction (64) | |||||||||
Map_info | Map | II | Position | 3.46624 | Error | 0.000275 | |||
Positive | Positive_clone | VW02B12L | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (27) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |