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WormBase Tree Display for Gene: WBGene00012156

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Name Class

WBGene00012156SMapS_parentSequenceVW02B12L
IdentityVersion2
NameCGC_nameebp-2Person_evidenceWBPerson1480
Sequence_nameVW02B12L.3
Molecular_nameVW02B12L.3
VW02B12L.3.1
CE18982
Other_nameCELE_VW02B12L.3Accession_evidenceNDBBX284602
Public_nameebp-2
DB_infoDatabaseAceViewgene2L733
WormQTLgeneWBGene00012156
WormFluxgeneWBGene00012156
NDBlocus_tagCELE_VW02B12L.3
PanthergeneCAEEL|WormBase=WBGene00012156|UniProtKB=Q9XXA2
familyPTHR10623
NCBIgene174744
RefSeqproteinNM_064037.7
TREEFAMTREEFAM_IDTF313620
TrEMBLUniProtAccQ9XXA2
UniProt_GCRPUniProtAccQ9XXA2
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
209 Jun 2005 10:01:00WBPerson2970Name_changeCGC_nameebp-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classebp
Allele (22)
StrainWBStrain00036705
WBStrain00036737
WBStrain00034624
WBStrain00007423
WBStrain00053560
RNASeq_FPKM (74)
GO_annotation (18)
Contained_in_operonCEOP2536
Ortholog (49)
ParalogWBGene00007062Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00013344Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionebp-2 encodes an RP/EB-type microtubule-binding protein orthologous to human MAPRE1 (OMIM:603108), MAPRE2 (OMIM:605789), MAPRE3 (OMIM:605788), and paralogous to EBP-1/-3; EBP-2 binds the plus ends of growing microtubules; by orthology, the N-terminal calponin homology domain of EBP-2 is predicted to bind microtubules (MTs), while the C-terminal region of EBP-2 is predicted to contain a dimerization domain and a site for binding protein ligands that activate EBP-2's MT-binding; ebp-2(RNAi) animals have no obvious phenotypes, perhaps because of genetic redundancy with ebp-1 and ebp-3.Paper_evidenceWBPaper00026660
WBPaper00031417
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated25 Jan 2014 00:00:00
Automated_descriptionPredicted to enable microtubule plus-end binding activity. Predicted to be involved in protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and non-motile cilium. Expressed in several structures, including hypodermis; nervous system; and ventral nerve cord.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSVW02B12L.3
Corresponding_transcriptVW02B12L.3.1
Other_sequence (12)
Associated_featureWBsf644680
WBsf222136
WBsf222137
WBsf222138
Experimental_infoRNAi_resultWBRNAi00054475Inferred_automaticallyRNAi_primary
WBRNAi00036123Inferred_automaticallyRNAi_primary
WBRNAi00019437Inferred_automaticallyRNAi_primary
WBRNAi00062390Inferred_automaticallyRNAi_primary
Expr_patternExpr3660
Expr3661
Expr13607
Expr16485
Expr1023670
Expr1035377
Expr1158021
Expr2011163
Expr2029399
Construct_product (12)
AntibodyWBAntibody00000867
Microarray_results (20)
Expression_cluster (125)
Interaction (64)
Map_infoMapIIPosition3.46624Error0.000275
PositivePositive_cloneVW02B12LInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (27)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene