WormBase Tree Display for Gene: WBGene00012005
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| WBGene00012005 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 4 | |||||||
| Name | CGC_name | jun-1 | Person_evidence | WBPerson2962 | |||||
| WBPerson443 | |||||||||
| Sequence_name | T24H10.7 | ||||||||
| Molecular_name (27) | |||||||||
| Other_name | CELE_T24H10.7 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | jun-1 | ||||||||
| DB_info | Database | AceView | gene | 2J421 | |||||
| WormQTL | gene | WBGene00012005 | |||||||
| WormFlux | gene | WBGene00012005 | |||||||
| NDB | locus_tag | CELE_T24H10.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00012005|UniProtKB=G5ECU7 | |||||||
| family | PTHR11462 | ||||||||
| NCBI | gene | 174452 | |||||||
| RefSeq | protein | NM_001356878.3 | |||||||
| NM_001356880.3 | |||||||||
| NM_001136355.4 | |||||||||
| NM_001356881.3 | |||||||||
| NM_001383910.2 | |||||||||
| NM_001356879.3 | |||||||||
| NM_001027195.4 | |||||||||
| NM_001027197.5 | |||||||||
| NM_001027196.5 | |||||||||
| SwissProt | UniProtAcc | G5ECU7 | |||||||
| TrEMBL | UniProtAcc | A0A2C9C3K0 | |||||||
| A0A2C9C3E7 | |||||||||
| A0A2C9C2T0 | |||||||||
| A0A2C9C2Y8 | |||||||||
| UniProt_GCRP | UniProtAcc | G5ECU7 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 29 Nov 2004 12:57:28 | WBPerson1983 | Event | Acquires_merge | WBGene00012001 | ||||
| 3 | 27 Apr 2007 10:10:56 | WBPerson1983 | Event | Acquires_merge | WBGene00012006 | ||||
| 4 | 07 Nov 2007 09:36:21 | WBPerson2970 | Name_change | CGC_name | jun-1 | ||||
| Acquires_merge | WBGene00012001 | ||||||||
| WBGene00012006 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | jun | ||||||||
| Allele (304) | |||||||||
| Strain | WBStrain00036395 | ||||||||
| WBStrain00036410 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (28) | |||||||||
| Contained_in_operon | CEOP2709 | ||||||||
| Ortholog (31) | |||||||||
| Structured_description | Concise_description | jun-1 encodes a basic-leucine zipper (bZIP) transcription factor that is the C. elegans JUN homolog; jun-1 activity is essential for regulation of ovulation, and thus normal levels of fertility; in regulating ovulation, JUN-1 functions with FOS-1 to regulate expression of plc-1 which encodes a phospholipase C essential for IP3 production and ovulation; in addition, JUN-1 interacts with FOS-1 in vitro to form heterodimers capable of binding upstream regulatory sequences of egl-13, which encodes a transcription factor required for uterine cell fate specification; jun-1 is expressed in the uterus and the spermatheca. | Paper_evidence | WBPaper00031111 | |||||
| WBPaper00034689 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 19 Jan 2010 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of RNA splicing; and response to starvation. Located in nucleus. Expressed in several structures, including excretory cell; hermaphrodite gonad; nervous system; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and lymphoma (multiple). Is an ortholog of human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); JUNB (JunB proto-oncogene, AP-1 transcription factor subunit); and JUND (JunD proto-oncogene, AP-1 transcription factor subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050861 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204,HGNC:6205) | ||||
| DOID:0050860 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:0050865 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204,HGNC:6205,HGNC:6206) | ||||||
| DOID:2957 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:0050866 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204,HGNC:6205) | ||||||
| DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||||
| DOID:3748 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||||
| DOID:2871 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:219 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||||
| DOID:10286 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:8567 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204,HGNC:6205) | ||||||
| DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:1686 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:0050744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||||
| DOID:2870 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:1909 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||||
| DOID:0050700 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6206) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6206) | ||||||
| DOID:5520 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||||
| DOID:2526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||||
| DOID:3121 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||||
| Molecular_info | Corresponding_CDS | T24H10.7a | |||||||
| T24H10.7b | |||||||||
| T24H10.7c | |||||||||
| T24H10.7d | |||||||||
| T24H10.7e | |||||||||
| T24H10.7f | |||||||||
| T24H10.7g | |||||||||
| T24H10.7h | |||||||||
| T24H10.7i | |||||||||
| Corresponding_CDS_history | T24H10.7:wp136 | ||||||||
| Corresponding_transcript | T24H10.7a.1 | ||||||||
| T24H10.7b.1 | |||||||||
| T24H10.7c.1 | |||||||||
| T24H10.7d.1 | |||||||||
| T24H10.7e.1 | |||||||||
| T24H10.7f.1 | |||||||||
| T24H10.7g.1 | |||||||||
| T24H10.7h.1 | |||||||||
| T24H10.7i.1 | |||||||||
| Other_sequence (42) | |||||||||
| Associated_feature (34) | |||||||||
| Gene_product_binds (375) | |||||||||
| Transcription_factor | WBTranscriptionFactor000109 | ||||||||
| WBTranscriptionFactor000501 | |||||||||
| Experimental_info | RNAi_result (33) | ||||||||
| Expr_pattern (14) | |||||||||
| Drives_construct | WBCnstr00012826 | ||||||||
| WBCnstr00014260 | |||||||||
| WBCnstr00014283 | |||||||||
| WBCnstr00014284 | |||||||||
| WBCnstr00014288 | |||||||||
| WBCnstr00014300 | |||||||||
| WBCnstr00014302 | |||||||||
| WBCnstr00030207 | |||||||||
| Construct_product | WBCnstr00030207 | ||||||||
| Microarray_results (48) | |||||||||
| Expression_cluster (184) | |||||||||
| Interaction (46) | |||||||||
| Map_info | Map | II | Position | 1.04759 | Error | 0.001496 | |||
| Positive | Positive_clone | T24H10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00025433 | ||||||||
| WBPaper00025575 | |||||||||
| WBPaper00028802 | |||||||||
| WBPaper00031111 | |||||||||
| WBPaper00033939 | |||||||||
| WBPaper00034543 | |||||||||
| WBPaper00034689 | |||||||||
| WBPaper00035989 | |||||||||
| WBPaper00039041 | |||||||||
| WBPaper00041960 | |||||||||
| WBPaper00042067 | |||||||||
| WBPaper00043072 | |||||||||
| WBPaper00044281 | |||||||||
| WBPaper00044399 | |||||||||
| WBPaper00046151 | |||||||||
| WBPaper00047745 | |||||||||
| WBPaper00049734 | |||||||||
| WBPaper00051455 | |||||||||
| WBPaper00051670 | |||||||||
| WBPaper00058109 | |||||||||
| WBPaper00060358 | |||||||||
| WBPaper00061115 | |||||||||
| WBPaper00064212 | |||||||||
| WBPaper00064229 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
