WormBase Tree Display for Gene: WBGene00011638

WBGene00011638 SMap: S_parent: Sequence: T09A5
  Identity: Version: 2
    Name: CGC_name: ostb-1 Person_evidence: WBPerson8
      Sequence_name: T09A5.11
      Molecular_name: T09A5.11
        T09A5.11.1
        CE01081
      Other_name: CELE_T09A5.11 Accession_evidence: NDB BX284602
      Public_name: ostb-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Sep 2009 14:42:50 WBPerson9133 Name_change: CGC_name: ostb-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ostb
    Allele (33)
    Strain: WBStrain00055469
    RNASeq_FPKM (74)
    GO_annotation: 00046223
      00046224
      00046225
      00046226
      00046227
      00046228
      00105785
      00118858
      00118859
    Ortholog (35)
    Structured_description: Automated_description: Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ir. Is an ortholog of human DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080569 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2728)
  Molecular_info: Corresponding_CDS: T09A5.11
    Corresponding_transcript: T09A5.11.1
    Other_sequence (71)
    Associated_feature (11)
  Experimental_info: RNAi_result (15)
    Expr_pattern: Expr1017386
      Expr1035126
      Expr1156518
      Expr2014654
      Expr2032887
    Drives_construct: WBCnstr00030510
    Construct_product: WBCnstr00030510
    Microarray_results (21)
    Expression_cluster: WBPaper00028451:Low_abundance_spermatogenesis_enriched
      WBPaper00032528:L3_enriched
      WBPaper00035073:mitochondria_protein
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038213:E.coli(LF82)_72h_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00040209:B.thuringiensis_upregulated_MY15
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044616:alg-3-4_upregulated_protein
      WBPaper00044736:flat_dev_expression
      WBPaper00045486:starvation_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049626:UNC-75_target
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:lin-15B(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053810:clk-1(qm30)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054189:aging_regulated_protein
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00059174:MEG-3_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059471:EGL-43_interacting
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059598:HeatShock_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061340:Coelomocyte
      WBPaper00061340:g1A
      WBPaper00061340:g1A_g1P
      WBPaper00061340:g1P
      WBPaper00061340:hmc_and_homolog
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:Y45F10D.7-C14C10.4
      WBPaper00061651:Excretory_gland_cell_enriched
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_downregulated_hypodermis
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064201:SNA-3_interacting
      WBPaper00064315:mes-4(bn73)_downregulated_PGCs
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F2
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065149:lin-52(n771)_upregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      cgc4386_cluster_5_3
      cgc4489_group_3
      WBPaper00025032:cluster_157
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00032948:FedUp
      WBPaper00035905:FBF-1_Associated
      WBPaper00037611:GLD-2-associated
      WBPaper00037611:RNP-8-associated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041207:CE_dauer_down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_24h
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (100)
  Map_info: Map: II Position: 0.589813 Error: 0.001296
    Positive: Positive_clone: T09A5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00029024
    WBPaper00038491
    WBPaper00045573
    WBPaper00049828
    WBPaper00055090
    WBPaper00059347
    WBPaper00060970
    WBPaper00064933
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene