Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00011083

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00011083SMapS_parentSequenceR07B1
IdentityVersion2
NameCGC_nameglo-1Person_evidenceWBPerson253
Sequence_nameR07B1.12
Molecular_nameR07B1.12
R07B1.12.1
CE38625
Other_nameCELE_R07B1.12Accession_evidenceNDBBX284606
Public_nameglo-1
DB_infoDatabaseAceViewgeneXK500
WormQTLgeneWBGene00011083
WormFluxgeneWBGene00011083
NDBlocus_tagCELE_R07B1.12
PanthergeneCAEEL|WormBase=WBGene00011083|UniProtKB=G5EBF0
familyPTHR24073
NCBIgene3565633
RefSeqproteinNM_001029666.3
TREEFAMTREEFAM_IDTF324491
TrEMBLUniProtAccG5EBF0
UniProt_GCRPUniProtAccG5EBF0
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
218 Jul 2005 17:06:47WBPerson2970Name_changeCGC_nameglo-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classglo
Allele (168)
StrainWBStrain00022488
WBStrain00005803
WBStrain00052447
WBStrain00055239
RNASeq_FPKM (74)
GO_annotation (21)
Ortholog (42)
Paralog (32)
Structured_descriptionConcise_descriptionglo-1 encodes a member of the Rab family of small GTPases that is similar to the vertebrate Rab32 and Rab38 proteins and Drosophila Rab-RP1/Lightoid; throughout development, glo-1 activity is required for biogenesis of the lysosome-related gut granules; in addition, glo-1 activity is required during embryonic development for normal body morphogenesis; in regulating gut granule formation, glo-1 acts downstream of apb-3 which encodes the AP-3 complex beta subunits; GLO-1 reporter fusions and antibodies indicate that GLO-1 is expressed in embryonic and adult intestinal cells, beginning at the E2 stage of intestinal development; within intestinal cells, GLO-1 colocalizes with lysosome-related gut granules.Paper_evidenceWBPaper00025094
Curator_confirmedWBPerson1843
Date_last_updated23 Jan 2007 00:00:00
Automated_descriptionPredicted to enable GTPase activity. Involved in lipid storage and lysosome organization. Located in gut granule membrane. Expressed in intestine. Is an ortholog of human RAB32 (RAB32, member RAS oncogene family).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR07B1.12
Corresponding_CDS_historyR07B1.12:wp143
Corresponding_transcriptR07B1.12.1
Other_sequence (16)
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00114320Inferred_automaticallyRNAi_primary
WBRNAi00051417Inferred_automaticallyRNAi_primary
Expr_patternExpr4747
Expr12822
Expr13997
Expr1021410
Expr1034866
Expr1155099
Expr2012105
Expr2030341
Drives_constructWBCnstr00006434
WBCnstr00012217
WBCnstr00017961
WBCnstr00030945
WBCnstr00041286
WBCnstr00041287
Construct_productWBCnstr00005941
WBCnstr00009015
WBCnstr00012217
WBCnstr00030945
WBCnstr00041287
AntibodyWBAntibody00001013
Microarray_results (17)
Expression_clusterWBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:intestine_CoreEnriched
WBPaper00037950:intestine_embryo_enriched
WBPaper00037950:intestine_embryo_SelectivelyEnriched
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_larva_enriched
WBPaper00037950:intestine_larva_SelectivelyEnriched
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00044736:flat_dev_expression
WBPaper00044760:somatic_specific
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045390:ubc-9(RNAi)_upregulated
WBPaper00045571:germline-ablation_upregulated
WBPaper00045861:ash-2(tm1095)_upregulated
WBPaper00045861:set-2(ok952)_upregulated
WBPaper00046121:endoderm_unique
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00050332:skn-1(RNAi)_downregulated
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:intestine_enriched
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00051245:cytoplasm_specific
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:intestine_specific
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053302:alovudine_24h_regulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053388:dauer_regulated_Cluster3
WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
WBPaper00053664:ins-11(tm1053)_downregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056161:hermaphrodite_enriched_siRNA
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057068:Cadmium_upregulated
WBPaper00058691:cfp-1(tm6369)_downregulated
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059839:S.maltophilia_regulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060445:nfki-1(cer1)_downregulated_L4
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061340:Intestine
WBPaper00061341:28C_24h_upregulated
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064632:daf-2(e1370)_upregulated_intestine
WBPaper00064716:paraquat_downregulated
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00065029:cadmium_upregulated
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
WBPaper00041174:environmental
WBPaper00041174:environmental_prime
InteractionWBInteraction000005480
WBInteraction000502755
WBInteraction000503374
WBInteraction000580741
Map_infoMapXPosition1.73076Error0.000103
PositivePositive_cloneR07B1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5634
Pseudo_map_position
Reference (55)
Remarkglo-1 was previously connected to WBGene00001608 [050818 mt3]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene