WormBase Tree Display for Gene: WBGene00011083
expand all nodes | collapse all nodes | view schema
| WBGene00011083 | SMap | S_parent | Sequence | R07B1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | glo-1 | Person_evidence | WBPerson253 | |||||
| Sequence_name | R07B1.12 | ||||||||
| Molecular_name | R07B1.12 | ||||||||
| R07B1.12.1 | |||||||||
| CE38625 | |||||||||
| Other_name | CELE_R07B1.12 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | glo-1 | ||||||||
| DB_info | Database | AceView | gene | XK500 | |||||
| WormQTL | gene | WBGene00011083 | |||||||
| WormFlux | gene | WBGene00011083 | |||||||
| NDB | locus_tag | CELE_R07B1.12 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00011083|UniProtKB=G5EBF0 | |||||||
| family | PTHR24073 | ||||||||
| NCBI | gene | 3565633 | |||||||
| RefSeq | protein | NM_001029666.3 | |||||||
| TREEFAM | TREEFAM_ID | TF324491 | |||||||
| TrEMBL | UniProtAcc | G5EBF0 | |||||||
| UniProt_GCRP | UniProtAcc | G5EBF0 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 18 Jul 2005 17:06:47 | WBPerson2970 | Name_change | CGC_name | glo-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | glo | ||||||||
| Allele (168) | |||||||||
| Strain | WBStrain00022488 | ||||||||
| WBStrain00005803 | |||||||||
| WBStrain00052447 | |||||||||
| WBStrain00055239 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (42) | |||||||||
| Paralog (32) | |||||||||
| Structured_description | Concise_description | glo-1 encodes a member of the Rab family of small GTPases that is similar to the vertebrate Rab32 and Rab38 proteins and Drosophila Rab-RP1/Lightoid; throughout development, glo-1 activity is required for biogenesis of the lysosome-related gut granules; in addition, glo-1 activity is required during embryonic development for normal body morphogenesis; in regulating gut granule formation, glo-1 acts downstream of apb-3 which encodes the AP-3 complex beta subunits; GLO-1 reporter fusions and antibodies indicate that GLO-1 is expressed in embryonic and adult intestinal cells, beginning at the E2 stage of intestinal development; within intestinal cells, GLO-1 colocalizes with lysosome-related gut granules. | Paper_evidence | WBPaper00025094 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 23 Jan 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTPase activity. Involved in lipid storage and lysosome organization. Located in gut granule membrane. Expressed in intestine. Is an ortholog of human RAB32 (RAB32, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R07B1.12 | |||||||
| Corresponding_CDS_history | R07B1.12:wp143 | ||||||||
| Corresponding_transcript | R07B1.12.1 | ||||||||
| Other_sequence (16) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00114320 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00051417 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4747 | ||||||||
| Expr12822 | |||||||||
| Expr13997 | |||||||||
| Expr1021410 | |||||||||
| Expr1034866 | |||||||||
| Expr1155099 | |||||||||
| Expr2012105 | |||||||||
| Expr2030341 | |||||||||
| Drives_construct | WBCnstr00006434 | ||||||||
| WBCnstr00012217 | |||||||||
| WBCnstr00017961 | |||||||||
| WBCnstr00030945 | |||||||||
| WBCnstr00041286 | |||||||||
| WBCnstr00041287 | |||||||||
| Construct_product | WBCnstr00005941 | ||||||||
| WBCnstr00009015 | |||||||||
| WBCnstr00012217 | |||||||||
| WBCnstr00030945 | |||||||||
| WBCnstr00041287 | |||||||||
| Antibody | WBAntibody00001013 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (86) | |||||||||
| Interaction | WBInteraction000005480 | ||||||||
| WBInteraction000502755 | |||||||||
| WBInteraction000503374 | |||||||||
| WBInteraction000580741 | |||||||||
| Map_info | Map | X | Position | 1.73076 | Error | 0.000103 | |||
| Positive | Positive_clone | R07B1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5634 | |||||||
| Pseudo_map_position | |||||||||
| Reference (55) | |||||||||
| Remark | glo-1 was previously connected to WBGene00001608 [050818 mt3] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
