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WormBase Tree Display for Gene: WBGene00010813

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Name Class

WBGene00010813SMapS_parentSequenceCHROMOSOME_III
IdentityVersion2
NameCGC_namepitp-1Person_evidenceWBPerson284
WBPerson433
Sequence_nameM01F1.7
Molecular_nameM01F1.7
M01F1.7.1
CE33673
Other_nameCELE_M01F1.7Accession_evidenceNDBBX284603
Public_namepitp-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
229 Oct 2010 15:41:12WBPerson2970Name_changeCGC_namepitp-1
Sequence_nameM01F1.7
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpitp
Allele (124)
StrainWBStrain00022698
WBStrain00022699
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (45)
ParalogWBGene00022155Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021854Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionpitp-1 encodes a phosphatidylinositol transfer protein, with a C-terminal DDHD domain, that is orthologous to RETINAL DEGENERATION B (RDGB) in D. melanogaster, as well as other orthologs in mammals (NIR1-3); pitp-1 is expressed in the egg membrane, the germline, the spermatheca and three pairs of head neurons; PITP-1 is predicted to mediate PIP(2) signalling in either neuronal function or cytokinesis.Paper_evidenceWBPaper00004403
WBPaper00004651
WBPaper00005654
WBPaper00012751
WBPaper00012871
WBPaper00013030
WBPaper00013086
WBPaper00013591
WBPaper00023591
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated08 Nov 2010 00:00:00
Automated_descriptionPredicted to enable phospholipid binding activity and phospholipid transporter activity. Predicted to be involved in intermembrane lipid transfer and phospholipid transport. Located in ciliary transition zone and synapse. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in cone-rod dystrophy 5. Is an ortholog of human PITPNM1 (phosphatidylinositol transfer protein membrane associated 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111010Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21043)
Molecular_infoCorresponding_CDSM01F1.7
Corresponding_CDS_historyM01F1.7:wp98
Corresponding_transcriptM01F1.7.1
Other_sequence (18)
Associated_feature (12)
Experimental_infoRNAi_resultWBRNAi00067300Inferred_automaticallyRNAi_primary
WBRNAi00017105Inferred_automaticallyRNAi_primary
WBRNAi00067057Inferred_automaticallyRNAi_primary
WBRNAi00050773Inferred_automaticallyRNAi_primary
WBRNAi00050774Inferred_automaticallyRNAi_primary
WBRNAi00085867Inferred_automaticallyRNAi_primary
WBRNAi00006068Inferred_automaticallyRNAi_primary
WBRNAi00034363Inferred_automaticallyRNAi_primary
WBRNAi00001081Inferred_automaticallyRNAi_primary
WBRNAi00007157Inferred_automaticallyRNAi_primary
Expr_patternExpr9287
Expr15667
Expr1016405
Expr1034740
Expr1154468
Expr2014936
Expr2033171
Drives_constructWBCnstr00008579
WBCnstr00008581
WBCnstr00013876
WBCnstr00031130
WBCnstr00042468
Construct_productWBCnstr00008581
WBCnstr00008585
WBCnstr00013876
WBCnstr00031130
Microarray_results (19)
Expression_cluster (143)
Interaction (15)
Map_infoMapIIIPosition-5.98197Error0.072065
PositivePositive_cloneM01F1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene