WormBase Tree Display for Gene: WBGene00010019

WBGene00010019 SMap: S_parent: Sequence: F54B8
  Identity: Version: 1
    Name: Sequence_name: F54B8.4
      Molecular_name: F54B8.4a
        F54B8.4a.1
        CE16106
        F54B8.4b
        CE47104
        F54B8.4b.1
      Other_name: CELE_F54B8.4 Accession_evidence: NDB BX284605
      Public_name: F54B8.4
    DB_info: Database: AceView gene 5Q295
        WormQTL gene WBGene00010019
        WormFlux gene WBGene00010019
        NDB locus_tag CELE_F54B8.4
        Panther gene CAEEL|WormBase=WBGene00010019|UniProtKB=H9G342
          family PTHR13177
        NCBI gene 186201
        RefSeq protein NM_001269756.3
            NM_001269755.3
        TrEMBL UniProtAcc O45562
            H9G342
        UniProt_GCRP UniProtAcc H9G342
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (17)
    RNASeq_FPKM (74)
    GO_annotation: 00023792
      00023793
      00023794
      00023795
      00034786
    Ortholog (25)
    Paralog: WBGene00012140 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: The F54B8.4 gene encodes a homolog of Death Associated Protein 1 (DAP-1) protein that may be involved in apoptosis. Paper_evidence: WBPaper00004589
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable death domain binding activity. Involved in innate immune response. Is an ortholog of human DAP (death associated protein). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F54B8.4a
      F54B8.4b
    Corresponding_transcript (2)
    Associated_feature: WBsf647609
      WBsf233051
  Experimental_info: RNAi_result: WBRNAi00048237 Inferred_automatically: RNAi_primary
      WBRNAi00032743 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1012461
      Expr1152043
      Expr2004117
      Expr2022341
    Drives_construct: WBCnstr00031735
    Construct_product: WBCnstr00031735
    Microarray_results (22)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035211:age-1_vs_N2_upregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_L3_downregulated
      WBPaper00040990:PA14_upregulated
      WBPaper00041163:hly(+)-V-cholerae_induced
      WBPaper00041954:ethanol_upregulated
      WBPaper00042034:NO_upregulated_hsf-1(sy441)
      WBPaper00042034:NO_upregulated_N2
      WBPaper00042194:nhr-114(RNAi)_downregulated
      WBPaper00042194:Tryptophan_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00043945:MeHg_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045390:tunicamycin_downregulated
      WBPaper00045390:ubc-9(RNAi)_downregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045486:starvation_downregulated
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046741:Garlic-Extract_downregulated_mRNA
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048988:neuron_expressed
      WBPaper00049001:EVN_enriched
      WBPaper00049018:swsn-2.2(RNAi)_downregulated
      WBPaper00049377:MWCNT_downregulated
      WBPaper00049489:AMsh-glia_enriched
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050193:dpy-27(RNAi)_upregulated_L1
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050561:indole_10-fold_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051021:4-bromodiphenyl-ether_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053154:human-amyloid-beta_tau_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(icb38)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053318:Aging_upregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053402:his-3(RNAi)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053810:sod-2(ok1030)_upregulated
      WBPaper00054191:H3.3(null)_L1_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_adult
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057196:raga-1(ok386)_upregulated)
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058599:benzimidazoles_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059175:hlh-17p-XBP-1_upregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_L1
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:CoCl2_6hr_upregulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060445:ikb-1(nr2027)_upregulated_L1
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061274:microgravity_downregulated
      WBPaper00061340:ADF
      WBPaper00061340:DVA
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:C10C5.2-Y58A7A.3
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061651:I2_enriched
      WBPaper00061952:daf-18(yh1)_downregulated
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062456:doxycycline_upregulated_CB4856_transcript
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00062590:Aging_upregulated_intestine
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064291:antimycin_upregulated
      WBPaper00064509:static-magnetic-field_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064999:miR-229-64-65-66_upregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065288:mdt-15(tm2182)_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065841:9_0
      WBPaper00065841:9_1
      WBPaper00065841:9_2
      WBPaper00065841:27_0
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      cgc4386_cluster_3_3
      cgc4489_group_17
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00028482:PA14_upregulated
      WBPaper00028789:PA14_vs_gacA_upregulated_4hr
      WBPaper00028789:PA14_vs_gacA_upregulated_8hr
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_8hr
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00031003:hlh_1_enriched
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035891:PA_induced_zip-2_dependent
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_D
      WBPaper00036383:ash-2_L3_regulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00041002:HF_11d_0.2mM_Down
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_prime
      WBPaper00041207:CE_dauer_up
      WBPaper00041211:RPW-24_Up
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_24h
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00044091:Bpseudomallei_induced_2h
      WBPaper00044091:Bpseudomallei_induced_4h
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_upregulated
      WBPaper00050650:mBmkTX_upregulated
      WBPaper00050767:Octopamine_induced
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
    Interaction: WBInteraction000428729
      WBInteraction000578361
      WBInteraction000580683
      WBInteraction000581850
      WBInteraction000584286
  Map_info: Positive: Positive_clone: F54B8 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: V 8.96134
  Method: Gene