WormBase Tree Display for Gene: WBGene00009701
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| WBGene00009701 | SMap | S_parent | Sequence | F44F4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | egg-3 | Person_evidence | WBPerson597 | |||||
| Sequence_name | F44F4.2 | ||||||||
| Molecular_name | F44F4.2 | ||||||||
| F44F4.2.1 | |||||||||
| CE00998 | |||||||||
| Other_name | CELE_F44F4.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | egg-3 | ||||||||
| DB_info | Database | AceView | gene | 2L174 | |||||
| WormQTL | gene | WBGene00009701 | |||||||
| WormFlux | gene | WBGene00009701 | |||||||
| NDB | locus_tag | CELE_F44F4.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00009701|UniProtKB=Q20402 | |||||||
| family | PTHR46163 | ||||||||
| NCBI | gene | 174677 | |||||||
| RefSeq | protein | NM_001383944.2 | |||||||
| SwissProt | UniProtAcc | Q20402 | |||||||
| UniProt_GCRP | UniProtAcc | Q20402 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 10 Sep 2007 09:53:41 | WBPerson2970 | Name_change | CGC_name | egg-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | egg | ||||||||
| Allele (33) | |||||||||
| Strain | WBStrain00037580 | ||||||||
| WBStrain00000053 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (25) | |||||||||
| Ortholog (35) | |||||||||
| Paralog (66) | |||||||||
| Structured_description | Concise_description | egg-3 encodes a member of the protein tyrosine phosphatase-like (PTPL) family; EGG-3 activity is required for proper regulation of the cell surface and cortical rearrangements that occur during egg activation in response to sperm entry; EGG-3 physically interacts with EGG-4/5 and the MBK-2 kinase to sequester MBK-2 at the oocyte cortex prior to meiosis, thus preventing MBK-2 from phosphorylating its substrates, such as cytoplasmic MEI-1/katanin; EGG-3 initially localizes to the oocyte cortex, but during anaphase of meiosis I moves into the cytoplasm where it is degraded allowing for activation of MBK-2. | Paper_evidence | WBPaper00031014 | |||||
| WBPaper00031015 | |||||||||
| WBPaper00035426 | |||||||||
| WBPaper00035427 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 26 Oct 2010 00:00:00 | ||||||||
| Automated_description | Enables protein kinase binding activity. Involved in cortical actin cytoskeleton organization; female gamete generation; and positive regulation of protein localization to cell cortex. Located in cell cortex. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F44F4.2 | |||||||
| Corresponding_transcript | F44F4.2.1 | ||||||||
| Other_sequence (18) | |||||||||
| Associated_feature | WBsf650528 | ||||||||
| WBsf666075 | |||||||||
| WBsf666076 | |||||||||
| WBsf976323 | |||||||||
| WBsf976324 | |||||||||
| WBsf976325 | |||||||||
| WBsf976326 | |||||||||
| WBsf223856 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr4904 | ||||||||
| Expr4905 | |||||||||
| Expr4907 | |||||||||
| Expr1021183 | |||||||||
| Expr1034243 | |||||||||
| Expr1151172 | |||||||||
| Expr2011201 | |||||||||
| Expr2029437 | |||||||||
| Drives_construct | WBCnstr00031981 | ||||||||
| Construct_product (11) | |||||||||
| Antibody | WBAntibody00001302 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (201) | |||||||||
| Interaction (307) | |||||||||
| Map_info | Map | II | Position | 3.13104 | Error | 9.7e-05 | |||
| Positive | Positive_clone | F44F4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (19) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
