WormBase Tree Display for Gene: WBGene00009701
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WBGene00009701 | SMap | S_parent | Sequence | F44F4 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | egg-3 | Person_evidence | WBPerson597 | |||
Sequence_name | F44F4.2 | ||||||
Molecular_name | F44F4.2 | ||||||
F44F4.2.1 | |||||||
CE00998 | |||||||
Other_name | CELE_F44F4.2 | Accession_evidence | NDB | BX284602 | |||
Public_name | egg-3 | ||||||
DB_info | Database | AceView | gene | 2L174 | |||
WormQTL | gene | WBGene00009701 | |||||
WormFlux | gene | WBGene00009701 | |||||
NDB | locus_tag | CELE_F44F4.2 | |||||
Panther | gene | CAEEL|WormBase=WBGene00009701|UniProtKB=Q20402 | |||||
family | PTHR46163 | ||||||
NCBI | gene | 174677 | |||||
RefSeq | protein | NM_001383944.2 | |||||
SwissProt | UniProtAcc | Q20402 | |||||
UniProt_GCRP | UniProtAcc | Q20402 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | egg | ||||||
Allele (33) | |||||||
Strain | WBStrain00037580 | ||||||
WBStrain00000053 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (25) | |||||||
Ortholog (35) | |||||||
Paralog (66) | |||||||
Structured_description | Concise_description | egg-3 encodes a member of the protein tyrosine phosphatase-like (PTPL) family; EGG-3 activity is required for proper regulation of the cell surface and cortical rearrangements that occur during egg activation in response to sperm entry; EGG-3 physically interacts with EGG-4/5 and the MBK-2 kinase to sequester MBK-2 at the oocyte cortex prior to meiosis, thus preventing MBK-2 from phosphorylating its substrates, such as cytoplasmic MEI-1/katanin; EGG-3 initially localizes to the oocyte cortex, but during anaphase of meiosis I moves into the cytoplasm where it is degraded allowing for activation of MBK-2. | Paper_evidence | WBPaper00031014 | |||
WBPaper00031015 | |||||||
WBPaper00035426 | |||||||
WBPaper00035427 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 26 Oct 2010 00:00:00 | ||||||
Automated_description | Enables protein kinase binding activity. Involved in cortical actin cytoskeleton organization; female gamete generation; and positive regulation of protein localization to cell cortex. Located in cell cortex. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F44F4.2 | |||||
Corresponding_transcript | F44F4.2.1 | ||||||
Other_sequence (18) | |||||||
Associated_feature | WBsf650528 | ||||||
WBsf666075 | |||||||
WBsf666076 | |||||||
WBsf976323 | |||||||
WBsf976324 | |||||||
WBsf976325 | |||||||
WBsf976326 | |||||||
WBsf223856 | |||||||
Experimental_info | RNAi_result (12) | ||||||
Expr_pattern | Expr4904 | ||||||
Expr4905 | |||||||
Expr4907 | |||||||
Expr1021183 | |||||||
Expr1034243 | |||||||
Expr1151172 | |||||||
Expr2011201 | |||||||
Expr2029437 | |||||||
Drives_construct | WBCnstr00031981 | ||||||
Construct_product (11) | |||||||
Antibody | WBAntibody00001302 | ||||||
Microarray_results (21) | |||||||
Expression_cluster (201) | |||||||
Interaction (307) | |||||||
Map_info | Map | II | Position | 3.13104 | Error | 9.7e-05 | |
Positive | Positive_clone | F44F4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (19) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |