WormBase Tree Display for Gene: WBGene00009552
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| WBGene00009552 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | piki-1 | Person_evidence | WBPerson3997 | |||||
| Sequence_name | F39B1.1 | ||||||||
| Molecular_name | F39B1.1 | ||||||||
| F39B1.1.1 | |||||||||
| CE05832 | |||||||||
| Other_name | CELE_F39B1.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | piki-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 07 Sep 2009 12:21:16 | WBPerson9133 | Name_change | CGC_name | piki-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | piki | ||||||||
| Allele (216) | |||||||||
| Strain | WBStrain00032504 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (36) | |||||||||
| Ortholog (42) | |||||||||
| Paralog | WBGene00000090 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00006932 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00018076 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00013557 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | piki-1 encodes a class II phosphatidylinositol 3-kinase (PI3K); piki-1 functions redundantly with vps-34 to regulate apoptotic cell clearance presumably through regulation of PtdIns(3)P levels. | Paper_evidence | WBPaper00035284 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 18 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in several processes, including phagosome maturation involved in apoptotic cell clearance; phosphatidylinositol-3-phosphate biosynthetic process; and positive regulation of phagocytosis, engulfment. Located in early phagosome and pseudopodium. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha) and PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8971,HGNC:8973) | ||||
| Molecular_info | Corresponding_CDS | F39B1.1 | |||||||
| Corresponding_transcript | F39B1.1.1 | ||||||||
| Other_sequence | Oden_isotig23030 | ||||||||
| JI164418.1 | |||||||||
| CBC14206_1 | |||||||||
| Oden_isotig18913 | |||||||||
| Dviv_isotig10407 | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00092313 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00092315 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023459 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014591 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00087661 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092314 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046751 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065088 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065087 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031974 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1013863 | ||||||||
| Expr1034175 | |||||||||
| Expr1150625 | |||||||||
| Expr2014928 | |||||||||
| Expr2033163 | |||||||||
| Drives_construct | WBCnstr00032105 | ||||||||
| Construct_product | WBCnstr00032105 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (102) | |||||||||
| Interaction (34) | |||||||||
| WBProcess | WBbiopr:00000015 | ||||||||
| Map_info | Map | X | Position | 22.2931 | Error | 0.008224 | |||
| Positive | Positive_clone | F39B1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (17) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
