WormBase Tree Display for Gene: WBGene00009448
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| WBGene00009448 | SMap | S_parent | Sequence | F35H8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | zfp-2 | Person_evidence | WBPerson2214 | |||||
| WBPerson585 | |||||||||
| Sequence_name | F35H8.3 | ||||||||
| Molecular_name | F35H8.3 | ||||||||
| F35H8.3.1 | |||||||||
| CE00981 | |||||||||
| Other_name | CELE_F35H8.3 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | zfp-2 | ||||||||
| DB_info | Database | AceView | gene | 2J849 | |||||
| WormQTL | gene | WBGene00009448 | |||||||
| WormFlux | gene | WBGene00009448 | |||||||
| NDB | locus_tag | CELE_F35H8.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00009448|UniProtKB=Q20082 | |||||||
| family | PTHR24393 | ||||||||
| NCBI | gene | 174505 | |||||||
| RefSeq | protein | NM_063654.6 | |||||||
| SwissProt | UniProtAcc | Q20082 | |||||||
| TREEFAM | TREEFAM_ID | TF350994 | |||||||
| UniProt_GCRP | UniProtAcc | Q20082 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 02 Mar 2006 11:42:04 | WBPerson2970 | Name_change | CGC_name | zfp-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | zfp | ||||||||
| Allele (34) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00067085 | ||||||||
| 00067086 | |||||||||
| 00067087 | |||||||||
| 00067088 | |||||||||
| 00067089 | |||||||||
| 00067090 | |||||||||
| 00067091 | |||||||||
| 00067092 | |||||||||
| 00067093 | |||||||||
| Ortholog (32) | |||||||||
| Paralog (16) | |||||||||
| Structured_description | Concise_description | zfp-2 encodes a zinc-finger transcription factor; loss of zfp-2 and lin-35/Rb results in almost complete sterility accompanied by defects in somatic gonad development and vulval morphology, as well as polyploidization of somatic cell nuclei; loss of zfp-2 activity by itself reveals that zfp-2 is also required for cosuppression, inhibition of RNAi of some genes, and wild-type levels of expression of a rol-6 extrachromosomal array; a zfp-2::GFP promoter fusion construct is expressed in vulval cells and all somatic gonad structures, such as the spermatheca, sheath cells, uterine cells and distal tip cells (DTCs). | Paper_evidence | WBPaper00025139 | |||||
| WBPaper00029258 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 14 Jan 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in body wall musculature; hermaphrodite gonad; pharynx; seam cell; and vulva. Is an ortholog of human ZBTB32 (zinc finger and BTB domain containing 32). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F35H8.3 | |||||||
| Corresponding_transcript | F35H8.3.1 | ||||||||
| Other_sequence (23) | |||||||||
| Associated_feature | WBsf644574 | ||||||||
| WBsf978441 | |||||||||
| WBsf989074 | |||||||||
| WBsf221897 | |||||||||
| WBsf221898 | |||||||||
| WBsf221899 | |||||||||
| Transcription_factor | WBTranscriptionFactor000230 | ||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr4593 | ||||||||
| Expr7541 | |||||||||
| Expr1016356 | |||||||||
| Expr1034134 | |||||||||
| Expr1150301 | |||||||||
| Expr2018129 | |||||||||
| Expr2036266 | |||||||||
| Drives_construct | WBCnstr00012102 | ||||||||
| WBCnstr00012686 | |||||||||
| WBCnstr00032175 | |||||||||
| Construct_product | WBCnstr00017962 | ||||||||
| WBCnstr00021768 | |||||||||
| WBCnstr00032175 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (134) | |||||||||
| Interaction (104) | |||||||||
| Map_info | Map | II | Position | 1.58987 | Error | 0.007886 | |||
| Positive | Positive_clone | F35H8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026592 | ||||||||
| WBPaper00029258 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
