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WormBase Tree Display for Gene: WBGene00009448

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Name Class

WBGene00009448SMapS_parentSequenceF35H8
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classzfp
Allele (34)
RNASeq_FPKM (74)
GO_annotation00067085
00067086
00067087
00067088
00067089
00067090
00067091
00067092
00067093
Ortholog (32)
Paralog (16)
Structured_descriptionConcise_descriptionzfp-2 encodes a zinc-finger transcription factor; loss of zfp-2 and lin-35/Rb results in almost complete sterility accompanied by defects in somatic gonad development and vulval morphology, as well as polyploidization of somatic cell nuclei; loss of zfp-2 activity by itself reveals that zfp-2 is also required for cosuppression, inhibition of RNAi of some genes, and wild-type levels of expression of a rol-6 extrachromosomal array; a zfp-2::GFP promoter fusion construct is expressed in vulval cells and all somatic gonad structures, such as the spermatheca, sheath cells, uterine cells and distal tip cells (DTCs).Paper_evidenceWBPaper00025139
WBPaper00029258
Curator_confirmedWBPerson1843
Date_last_updated14 Jan 2008 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in body wall musculature; hermaphrodite gonad; pharynx; seam cell; and vulva. Is an ortholog of human ZBTB32 (zinc finger and BTB domain containing 32).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF35H8.3
Corresponding_transcriptF35H8.3.1
Other_sequence (23)
Associated_featureWBsf644574
WBsf978441
WBsf989074
WBsf221897
WBsf221898
WBsf221899
Transcription_factorWBTranscriptionFactor000230
Experimental_infoRNAi_result (13)
Expr_patternExpr4593
Expr7541
Expr1016356
Expr1034134
Expr1150301
Expr2018129
Expr2036266
Drives_constructWBCnstr00012102
WBCnstr00012686
WBCnstr00032175
Construct_productWBCnstr00017962
WBCnstr00021768
WBCnstr00032175
Microarray_results (19)
Expression_cluster (134)
Interaction (104)
Map_infoMapIIPosition1.58987Error0.007886
PositivePositive_cloneF35H8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026592
WBPaper00029258
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene