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WormBase Tree Display for Gene: WBGene00009304

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Name Class

WBGene00009304SMapS_parentSequenceF32A7
IdentityVersion3
NameCGC_nameeva-1Paper_evidenceWBPaper00031043
Person_evidenceWBPerson2189
WBPerson893
Sequence_nameF32A7.3
Molecular_name (12)
Other_nametag-271
CELE_F32A7.3Accession_evidenceNDBBX284601
Public_nameeva-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:50WBPerson1971EventImportedInitial conversion from CDS class of WS125
222 Apr 2005 11:55:18WBPerson2970Name_changeCGC_nametag-271
309 Oct 2007 15:40:26WBPerson2970Name_changeCGC_nameeva-1
Other_nametag-271
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classeva
AlleleWBVar01915638
WBVar00309678
WBVar00102114
WBVar01499908
WBVar01476724
WBVar01557764
WBVar01557765
WBVar00543290
WBVar01499739
WBVar00162581
WBVar00162582
WBVar00162583
WBVar00162584
WBVar01231859
WBVar00162585
WBVar01231862
WBVar00162586
WBVar01231865
WBVar00162587
WBVar00162588
WBVar01231867
WBVar01231868
WBVar00162589
WBVar00162590
WBVar01231870
WBVar00162591
WBVar01231871
WBVar01231872
WBVar01493322
WBVar01290558
WBVar02125824
WBVar01236451
WBVar01891290
WBVar01715227
WBVar01499627
WBVar01499628
WBVar00145284
WBVar00249996
WBVar01499999
WBVar00353342
WBVar00353343
WBVar01499823
WBVar00353344
WBVar00353345
WBVar00353346
WBVar00353347
WBVar00353348
WBVar00353349
WBVar00259411
WBVar00353350
WBVar00353351
WBVar02150818
WBVar00353352
WBVar00353353
WBVar00353354
WBVar00694234
WBVar00353355
WBVar00353356
WBVar00694235
WBVar02150824
WBVar00353357
WBVar00694236
WBVar00694237
WBVar00694238
WBVar00694239
WBVar00694240
WBVar00694241
WBVar00694242
WBVar00694243
WBVar00694244
WBVar00694245
WBVar00694246
WBVar00694247
WBVar00694248
WBVar01499298
WBVar00694249
WBVar00694250
WBVar00694251
WBVar00694252
WBVar00694253
WBVar00092398
WBVar00694254
WBVar00694255
WBVar00694256
WBVar00694257
WBVar00694258
WBVar01498939
WBVar00694260
WBVar00694261
WBVar00694262
WBVar00694263
WBVar01412336
WBVar00694264
WBVar00694265
WBVar00694266
WBVar00694267
WBVar00694268
WBVar00694269
WBVar00694270
StrainWBStrain00036134
WBStrain00054912
RNASeq_FPKM (74)
GO_annotation00002163
00101597
00101598
00101599
00101600
00101601
00101602
00117029
Ortholog (33)
ParalogWBGene00002251Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00002252Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00007664Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00014035Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00015735Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00017947Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00017948Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioneva-1 encodes, by alternative splicing, two isoforms of a cell-surface protein that acts cell-autonomously with SAX-3 as a SLT-1 receptor subunit, and is required for guidance of the AVM pioneer axon to the ventral nerve cord; EVA-1's long isoform is predicted to have a signal sequence, an ectodomain with two lectinlike galactose-binding sequences, a single transmembrane sequence, and a cytodomain with a phosphotyrosine binding motif; homologs of EVA-1 include human C21orf63; EVA-1 is expressed in embryonic neurons during axonal growth, head and tail neurons, the ventral nerve cord, pharyngeal and body wall muscles, hypodermis, uterus and vulva; ectopic EVA-1 expression in touch-receptor neurons causes the cell body of ALM to be displaced anteriorly (due to failed posterior migration) in a SLT-1-dependent manner; the cytodomain of EVA-1 is functionally dispensable in vivo; eva-1 mutants enhance the ventral-axon guidance defects of unc-40 mutants; EVA-1, SLT-1, and SAX-3 bind one another in vitro.Paper_evidenceWBPaper00031043
Curator_confirmedWBPerson567
Date_last_updated29 Dec 2007 00:00:00
Automated_descriptionPredicted to enable carbohydrate binding activity. Located in M band; cell junction; and striated muscle dense body. Expressed in body wall musculature; hypodermis; pharyngeal muscle cell; and ventral nerve cord. Is an ortholog of human EVA1C (eva-1 homolog C).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF32A7.3a
F32A7.3b
F32A7.3c
Corresponding_CDS_historyF32A7.3a:wp114
F32A7.3b:wp114
Corresponding_transcriptF32A7.3a.1
F32A7.3b.1
F32A7.3b.2
F32A7.3b.3
F32A7.3b.4
F32A7.3c.1
Other_sequenceOden_isotig19651
FD514519.1
CJC06290_1
CRC10951_1
CBC04911_1
CSC00310_1
Associated_feature (13)
Experimental_infoRNAi_resultWBRNAi00109732Inferred_automaticallyRNAi_primary
WBRNAi00066624Inferred_automaticallyRNAi_primary
WBRNAi00046088Inferred_automaticallyRNAi_primary
WBRNAi00109779Inferred_automaticallyRNAi_primary
WBRNAi00109638Inferred_automaticallyRNAi_primary
WBRNAi00101830Inferred_automaticallyRNAi_primary
WBRNAi00031650Inferred_automaticallyRNAi_primary
WBRNAi00116608Inferred_automaticallyRNAi_primary
WBRNAi00003551Inferred_automaticallyRNAi_primary
WBRNAi00109685Inferred_automaticallyRNAi_primary
Expr_patternExpr4895
Expr9367
Expr1015991
Expr1034065
Expr1149975
Expr2011386
Expr2029622
Drives_constructWBCnstr00012316
WBCnstr00019877
WBCnstr00032298
Construct_productWBCnstr00012316
WBCnstr00013932
WBCnstr00019586
WBCnstr00019593
WBCnstr00019594
WBCnstr00032298
AntibodyWBAntibody00001309
Microarray_results (30)
Expression_cluster (229)
InteractionWBInteraction000028967
WBInteraction000262189
WBInteraction000524192
WBInteraction000543558
WBInteraction000551356
WBInteraction000551357
WBInteraction000551359
WBInteraction000555696
WBInteraction000555697
WBInteraction000555698
Map_infoMapIPosition27.9483Error0.004097
PositivePositive_cloneF32A7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5192
Pseudo_map_position
Reference (15)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene