WormBase Tree Display for Gene: WBGene00009245
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WBGene00009245 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 4 | |||||||
Name | CGC_name | rict-1 | Person_evidence | WBPerson7217 | |||||
WBPerson545 | |||||||||
Sequence_name | F29C12.3 | ||||||||
Molecular_name | F29C12.3a | ||||||||
F29C12.3a.1 | |||||||||
CE43301 | |||||||||
F29C12.3b | |||||||||
CE45435 | |||||||||
F29C12.3c | |||||||||
CE45505 | |||||||||
F29C12.3b.1 | |||||||||
F29C12.3c.1 | |||||||||
Other_name | lpo-6 | Paper_evidence | WBPaper00032966 | ||||||
CELE_F29C12.3 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | rict-1 | ||||||||
DB_info | Database | AceView | gene | 2N388 | |||||
WormQTL | gene | WBGene00009245 | |||||||
WormFlux | gene | WBGene00009245 | |||||||
NDB | locus_tag | CELE_F29C12.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00009245|UniProtKB=G5EFN2 | |||||||
family | PTHR13298 | ||||||||
NCBI | gene | 3565035 | |||||||
RefSeq | protein | NM_001267449.3 | |||||||
NM_001267447.2 | |||||||||
NM_001267448.2 | |||||||||
TREEFAM | TREEFAM_ID | TF343656 | |||||||
TrEMBL | UniProtAcc | G5ED67 | |||||||
G5EFN2 | |||||||||
G5EFK2 | |||||||||
UniProt_GCRP | UniProtAcc | G5EFN2 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 10 Oct 2005 16:20:12 | WBPerson1983 | Event | Acquires_merge | WBGene00009244 | ||||
3 | 28 Jan 2009 13:52:54 | WBPerson2970 | Name_change | CGC_name | rict-1 | ||||
4 | 22 Apr 2009 15:16:42 | WBPerson9133 | Name_change | Other_name | lpo-6 | ||||
Acquires_merge | WBGene00009244 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rict | ||||||||
Allele (535) | |||||||||
Strain | WBStrain00023647 | ||||||||
WBStrain00023655 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (12) | |||||||||
Ortholog (61) | |||||||||
Structured_description | Concise_description | rict-1 enocdes the C. elegans ortholog of mammalian Rictor, a component of the target of rapamycin complex 2 (TORC2); in C. elegans, rict-1 activity is required for regulation of fat metabolism, feeding, growth, and life span; rict-1 has been reported to interact genetically with akt-1, akt-2, and sgk-1; a rict-1::RFP promoter fusion indicates that rict-1 is expressed in head neurons, the ventral nerve cord, the intestine, body wall muscle, pharynx, and spermatheca. | Paper_evidence | WBPaper00032936 | |||||
WBPaper00032966 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Aug 2011 00:00:00 | ||||||||
Automated_description | Predicted to enable protein serine/threonine kinase activator activity. Involved in mesendoderm development. Part of TORC2 complex. Expressed in several structures, including head neurons; intestine; pharynx; spermatheca; and ventral nerve cord. Human ortholog(s) of this gene implicated in breast ductal carcinoma; gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of human RICTOR (RPTOR independent companion of MTOR complex 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (12) | ||||||||
Molecular_info | Corresponding_CDS | F29C12.3a | |||||||
F29C12.3b | |||||||||
F29C12.3c | |||||||||
Corresponding_CDS_history | F29C12.3:wp150 | ||||||||
F29C12.3:wp196 | |||||||||
Corresponding_transcript | F29C12.3a.1 | ||||||||
F29C12.3b.1 | |||||||||
F29C12.3c.1 | |||||||||
Other_sequence (17) | |||||||||
Associated_feature (20) | |||||||||
Experimental_info | RNAi_result (17) | ||||||||
Expr_pattern | Expr8566 | ||||||||
Expr8569 | |||||||||
Expr1021765 | |||||||||
Expr1034033 | |||||||||
Expr1149811 | |||||||||
Expr2015350 | |||||||||
Expr2033584 | |||||||||
Drives_construct | WBCnstr00005615 | ||||||||
WBCnstr00013366 | |||||||||
WBCnstr00013367 | |||||||||
Construct_product (12) | |||||||||
Microarray_results (30) | |||||||||
Expression_cluster (136) | |||||||||
Interaction (32) | |||||||||
WBProcess | WBbiopr:00000001 | ||||||||
Map_info | Map | II | Position | 14.309 | Error | 0.044756 | |||
Positive | Positive_clone | F29C12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (39) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |