WormBase Tree Display for Gene: WBGene00008878
expand all nodes | collapse all nodes | view schema
| WBGene00008878 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | ppfr-1 | Person_evidence | WBPerson399 | |||||
| Sequence_name | F16A11.3 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_F16A11.3 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | ppfr-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 23 Jul 2004 17:07:37 | WBPerson1847 | Event | Acquires_merge | WBGene00010861 | ||||
| 3 | 24 Apr 2007 09:47:20 | WBPerson2970 | Name_change | CGC_name | ppfr-1 | ||||
| Acquires_merge | WBGene00010861 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ppfr | ||||||||
| Allele (329) | |||||||||
| Strain | WBStrain00055488 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Contained_in_operon | CEOP1932 | ||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00003901 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ppfr-1 encodes a protein phosphatase regulatory subunit; PPFR-1 functions as a regulatory subunit of a protein phosphatase 4 complex that regulates the phosphorylation status, and activity of, the MEI-1/katanin microtubule severing activity during meiosis; ppfr-1(RNAi) in wild-type animals results in fertility defects in F1 hermaphrodites, who exhibit a 90-95% decrease in the total number of eggs laid; PPFR-1 physically interacts with MEL-26, a substrate recognition subunit for the CUL-3 E3 ubiquitin ligase that also physically interacts with MEI-1; PPFR-1 is localized to the cytoplasm. | Paper_evidence | WBPaper00005456 | |||||
| WBPaper00044012 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 22 Aug 2014 00:00:00 | ||||||||
| Automated_description | Enables protein domain specific binding activity and protein phosphatase activator activity. Involved in embryo development; organelle organization; and regulation of spindle elongation. Located in cytoplasm. Expressed in several structures, including intestine; neurons; pharynx; ventral nerve cord; and vulval muscle. Is an ortholog of human PPP4R1 (protein phosphatase 4 regulatory subunit 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F16A11.3a | |||||||
| F16A11.3b | |||||||||
| F16A11.3c | |||||||||
| F16A11.3d | |||||||||
| Corresponding_CDS_history | F16A11.3:wp129 | ||||||||
| F16A11.3d:wp210 | |||||||||
| Corresponding_transcript | F16A11.3a.1 | ||||||||
| F16A11.3b.1 | |||||||||
| F16A11.3c.1 | |||||||||
| F16A11.3d.1 | |||||||||
| Other_sequence | ACC04203_1 | ||||||||
| CJC05434_1 | |||||||||
| Oden_isotig18719 | |||||||||
| SSC06462_1 | |||||||||
| EX542372.1 | |||||||||
| EX545977.1 | |||||||||
| Dviv_isotig05100 | |||||||||
| JI473048.1 | |||||||||
| Associated_feature (54) | |||||||||
| Experimental_info | RNAi_result (22) | ||||||||
| Expr_pattern | Expr12854 | ||||||||
| Expr1011755 | |||||||||
| Expr1033871 | |||||||||
| Expr1148738 | |||||||||
| Expr2015006 | |||||||||
| Expr2033241 | |||||||||
| Drives_construct | WBCnstr00022905 | ||||||||
| Antibody | WBAntibody00002456 | ||||||||
| Microarray_results (45) | |||||||||
| Expression_cluster (133) | |||||||||
| Interaction (39) | |||||||||
| Map_info | Map | I | Position | 3.75752 | Error | 0.000624 | |||
| Positive | Positive_clone | F16A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026065 | ||||||||
| WBPaper00032438 | |||||||||
| WBPaper00033577 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00044012 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061619 | |||||||||
| WBPaper00062623 | |||||||||
| WBPaper00063115 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
