WormBase Tree Display for Gene: WBGene00008878
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WBGene00008878 | SMap | S_parent | Sequence | CHROMOSOME_I | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ppfr | ||||||
Allele (329) | |||||||
Strain | WBStrain00055488 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Contained_in_operon | CEOP1932 | ||||||
Ortholog (36) | |||||||
Paralog | WBGene00003901 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
Structured_description | Concise_description | ppfr-1 encodes a protein phosphatase regulatory subunit; PPFR-1 functions as a regulatory subunit of a protein phosphatase 4 complex that regulates the phosphorylation status, and activity of, the MEI-1/katanin microtubule severing activity during meiosis; ppfr-1(RNAi) in wild-type animals results in fertility defects in F1 hermaphrodites, who exhibit a 90-95% decrease in the total number of eggs laid; PPFR-1 physically interacts with MEL-26, a substrate recognition subunit for the CUL-3 E3 ubiquitin ligase that also physically interacts with MEI-1; PPFR-1 is localized to the cytoplasm. | Paper_evidence | WBPaper00005456 | |||
WBPaper00044012 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 22 Aug 2014 00:00:00 | ||||||
Automated_description | Enables protein domain specific binding activity and protein phosphatase activator activity. Involved in embryo development; organelle organization; and regulation of spindle elongation. Located in cytoplasm. Expressed in several structures, including intestine; neurons; pharynx; ventral nerve cord; and vulval muscle. Is an ortholog of human PPP4R1 (protein phosphatase 4 regulatory subunit 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F16A11.3a | |||||
F16A11.3b | |||||||
F16A11.3c | |||||||
F16A11.3d | |||||||
Corresponding_CDS_history | F16A11.3:wp129 | ||||||
F16A11.3d:wp210 | |||||||
Corresponding_transcript | F16A11.3a.1 | ||||||
F16A11.3b.1 | |||||||
F16A11.3c.1 | |||||||
F16A11.3d.1 | |||||||
Other_sequence | ACC04203_1 | ||||||
CJC05434_1 | |||||||
Oden_isotig18719 | |||||||
SSC06462_1 | |||||||
EX542372.1 | |||||||
EX545977.1 | |||||||
Dviv_isotig05100 | |||||||
JI473048.1 | |||||||
Associated_feature (54) | |||||||
Experimental_info | RNAi_result (22) | ||||||
Expr_pattern | Expr12854 | ||||||
Expr1011755 | |||||||
Expr1033871 | |||||||
Expr1148738 | |||||||
Expr2015006 | |||||||
Expr2033241 | |||||||
Drives_construct | WBCnstr00022905 | ||||||
Antibody | WBAntibody00002456 | ||||||
Microarray_results (45) | |||||||
Expression_cluster (133) | |||||||
Interaction (39) | |||||||
Map_info | Map | I | Position | 3.75752 | Error | 0.000624 | |
Positive | Positive_clone | F16A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00026065 | ||||||
WBPaper00032438 | |||||||
WBPaper00033577 | |||||||
WBPaper00038491 | |||||||
WBPaper00044012 | |||||||
WBPaper00055090 | |||||||
WBPaper00061619 | |||||||
WBPaper00062623 | |||||||
WBPaper00063115 | |||||||
WBPaper00064339 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |