WormBase Tree Display for Gene: WBGene00008810
expand all nodes | collapse all nodes | view schema
| WBGene00008810 | SMap | S_parent | Sequence | F14F7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyp-13A12 | |||||||
| Sequence_name | F14F7.3 | ||||||||
| Molecular_name | F14F7.3 | ||||||||
| F14F7.3.1 | |||||||||
| CE15823 | |||||||||
| Other_name | CELE_F14F7.3 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | cyp-13A12 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-13A12 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyp | ||||||||
| Allele (69) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00030758 | ||||||||
| 00030759 | |||||||||
| 00030760 | |||||||||
| 00116657 | |||||||||
| 00116658 | |||||||||
| 00116659 | |||||||||
| 00116660 | |||||||||
| Ortholog (92) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | cyp-13A12 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates. | Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 20 Nov 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in marginal cell. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8552 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||
| DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
| DOID:2987 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
| DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:0112251 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
| DOID:0080630 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:10825 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
| Molecular_info | Corresponding_CDS | F14F7.3 | |||||||
| Corresponding_transcript | F14F7.3.1 | ||||||||
| Other_sequence (45) | |||||||||
| Associated_feature | WBsf225958 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00013295 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00006998 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006134 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044623 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044622 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092629 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11129 | ||||||||
| Expr1016733 | |||||||||
| Expr1148590 | |||||||||
| Expr2010680 | |||||||||
| Expr2028920 | |||||||||
| Drives_construct | WBCnstr00017888 | ||||||||
| WBCnstr00017889 | |||||||||
| WBCnstr00017890 | |||||||||
| WBCnstr00018006 | |||||||||
| WBCnstr00018007 | |||||||||
| WBCnstr00032667 | |||||||||
| Construct_product | WBCnstr00017889 | ||||||||
| WBCnstr00017890 | |||||||||
| WBCnstr00018007 | |||||||||
| WBCnstr00032667 | |||||||||
| Microarray_results (14) | |||||||||
| Expression_cluster (199) | |||||||||
| Interaction (26) | |||||||||
| Map_info | Map | III | Position | 20.7523 | Error | 0.004784 | |||
| Positive | Positive_clone | F14F7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00042257 | |||||||||
| WBPaper00042573 | |||||||||
| WBPaper00043640 | |||||||||
| WBPaper00045624 | |||||||||
| WBPaper00047631 | |||||||||
| WBPaper00049920 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064598 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
