WormBase Tree Display for Gene: WBGene00008480

WBGene00008480 SMap: S_parent: Sequence: E04D5
  Identity: Version: 2
    Name: CGC_name: eif-2A Person_evidence: WBPerson2266
      Sequence_name: E04D5.1
      Molecular_name: E04D5.1a
        E04D5.1a.1
        CE37820
        E04D5.1b
        CE37821
        E04D5.1b.1
      Other_name: eIF2alpha Paper_evidence: WBPaper00048445
        CELE_E04D5.1 Accession_evidence: NDB BX284602
      Public_name: eif-2A
    DB_info: Database: AceView gene 2K709
        WormQTL gene WBGene00008480
        WormFlux gene WBGene00008480
        NDB locus_tag CELE_E04D5.1
        Panther gene CAEEL|WormBase=WBGene00008480|UniProtKB=Q19052
          family PTHR13227
        NCBI gene 174606
        RefSeq protein NM_001393177.1
            NM_063838.8
        SwissProt UniProtAcc Q19052
        TREEFAM TREEFAM_ID TF105866
        UniProt_GCRP UniProtAcc Q19052
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 09 Jan 2017 15:00:31 WBPerson2970 Name_change: CGC_name: eif-2A
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: eif
    Allele (39)
    Strain: WBStrain00002975
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (37)
    Paralog: WBGene00044632 Caenorhabditis elegans From_analysis: modENCODE_Pseudogenes
    Structured_description: Automated_description: Predicted to enable nucleic acid binding activity and ribosome binding activity. Involved in positive regulation of gene expression. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human EIF2A (eukaryotic translation initiation factor 2A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: E04D5.1a
      E04D5.1b
    Corresponding_CDS_history: E04D5.1a:wp136
      E04D5.1b:wp136
    Corresponding_transcript: E04D5.1a.1
      E04D5.1b.1
    Other_sequence (47)
    Associated_feature: WBsf644609
      WBsf981263
      WBsf222009
      WBsf222010
  Experimental_info: RNAi_result: WBRNAi00043669 Inferred_automatically: RNAi_primary
      WBRNAi00012683 Inferred_automatically: RNAi_primary
      WBRNAi00007759 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1259
      Expr5648
      Expr1025143
      Expr1033689
      Expr1147653
      Expr2011242
      Expr2029478
    Drives_construct (2)
    Construct_product: WBCnstr00032938
    Microarray_results (30)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:BAG-neuron_embryo_enriched
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00055013:HMG-3_interacting_protein
      WBPaper00055648:germline_expressed
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent
      WBPaper00056718:F01D4.5(baf20)_downregulated
      WBPaper00056826:SGP_biased
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00059174:MEG-3_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00061203:let-418(n3536)_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061340:M_cell
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:tars-1-AFFX-r2-3026-5_at
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062123:DEPS-1_interacting
      WBPaper00062123:GLH-1_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062293:clk-1(qm30)_downregulated
      WBPaper00062293:isp-1(qm150)_downregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064494:postdauer_downregulated_AWA
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065945:global-rpoa-2(-)_upregulated_transcript
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_3_5
      cgc4489_group_3
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025032:cluster_1
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031832:slr-2_regulated
      WBPaper00034739:N2moreDR1350
      WBPaper00035873:dpy-10_regulated
      WBPaper00037695:WC_5-day
      WBPaper00039866:ClassComp_daf-19_upregulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(53_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:oogenesis-enriched
    Interaction (72)
  Map_info: Positive: Positive_clone: E04D5 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II 2.5649
  Reference: WBPaper00035925
    WBPaper00038491
    WBPaper00048445
    WBPaper00055090
    WBPaper00055602
    WBPaper00059485
  Method: Gene