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WormBase Tree Display for Gene: WBGene00006960

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Name Class

WBGene00006960SMapS_parentSequenceF02D8
IdentityVersion1
NameCGC_namexbx-1Person_evidenceWBPerson641
Sequence_nameF02D8.3
Molecular_nameF02D8.3
F02D8.3.1
CE39142
Other_nameCELE_F02D8.3Accession_evidenceNDBBX284605
Public_namexbx-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:44WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classxbx
Allele (42)
StrainWBStrain00035263
WBStrain00022845
WBStrain00029248
WBStrain00007884
WBStrain00051699
RNASeq_FPKM (74)
GO_annotation (28)
Ortholog (36)
ParalogWBGene00001007
Structured_descriptionConcise_descriptionxbx-1 encodes a dynein light intermediate chain; XBX-1 activity is required for retrograde intraflagellar transport and thus, for proper formation of sensory neuron cilia; an XBX-1::YFP reporter fusion protein is found at the ciliary base and migrating along the ciliary axoneme in both anterograde and retrograde directions.Paper_evidenceWBPaper00005876
Curator_confirmedWBPerson1843
Date_last_updated13 Oct 2008 00:00:00
Automated_descriptionPredicted to enable dynein heavy chain binding activity. Involved in intraciliary retrograde transport and non-motile cilium assembly. Located in cilium. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Is an ortholog of human DYNC2LI1 (dynein cytoplasmic 2 light intermediate chain 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050592Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:24595)
Molecular_infoCorresponding_CDSF02D8.3
Corresponding_CDS_historyF02D8.3:wp149
Corresponding_transcriptF02D8.3.1
Other_sequenceDviv_isotig30908
JI211951.1
Oden_isotig26852
MJC01881_1
Acan_isotig12104
Oden_isotig26837
Associated_featureWBsf042309
WBsf647560
WBsf232973
Experimental_infoRNAi_resultWBRNAi00095208Inferred_automaticallyRNAi_primary
WBRNAi00043811Inferred_automaticallyRNAi_primary
WBRNAi00030573Inferred_automaticallyRNAi_primary
Expr_patternChronogram2007
Expr2565
Expr7495
Expr10110
Expr15054
Expr1021125
Expr1032971
Expr1147784
Expr2018090
Expr2036228
Drives_constructWBCnstr00001055
WBCnstr00006703
WBCnstr00012640
WBCnstr00034069
Construct_productWBCnstr00010855
WBCnstr00015624
WBCnstr00022309
WBCnstr00034069
WBCnstr00041890
Microarray_results (19)
Expression_cluster (118)
Interaction (23)
Map_infoMapVPosition7.10548Error0.010124
PositivePositive_cloneF02D8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4402
4759
Pseudo_map_position
Reference (47)
RemarkSequence connection from [Swoboda P, Adler HT, Thomas JH], 02/06/12 krb.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene