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WormBase Tree Display for Gene: WBGene00006954

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Name Class

WBGene00006954SMapS_parentSequenceCHROMOSOME_V
IdentityVersion1
NameCGC_namewrt-8Person_evidenceWBPerson83
Sequence_nameC29F3.2
Molecular_nameC29F3.2
C29F3.2.1
CE29200
Other_namecm20F10Paper_evidenceWBPaper00002823
CELE_C29F3.2Accession_evidenceNDBBX284605
Public_namewrt-8
DB_infoDatabaseAceViewgene5P822
WormQTLgeneWBGene00006954
WormFluxgeneWBGene00006954
NDBlocus_tagCELE_C29F3.2
PanthergeneCAEEL|WormBase=WBGene00006954|UniProtKB=Q94130
familyPTHR46706
NCBIgene180035
RefSeqproteinNM_074404.6
SwissProtUniProtAccQ94130
TREEFAMTREEFAM_IDTF316084
UniProt_GCRPUniProtAccQ94130
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classwrt
Allele (43)
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (25)
Paralog (24)
Structured_descriptionConcise_descriptionwrt-8 encodes a hedgehog-like protein, with (from N- to C-terminus) asignal sequence, a Wart domain, an short region of low-complexitysequence, and a Hint/Hog domain; WRT-8 is strongly expressed inhypodermal syncytia hyp6-hyp10 throughout life, and in in 12 subventralP cells and their descendants from 3-fold embryo to L2 larva stages; theHint/Hog domain is predicted to cut WRT-8 into two halves and thencovalently link cholesterol to the C-terminus of the Wart domain; theWart domain is predicted to form a cysteine-crosslinked protein involvedin intercellular signalling, and it has subtle similarity to theN-terminal Hedge domain of HEDGEHOG proteins; WRT-8 has no obviousfunction in RNAi assays.Paper_evidenceWBPaper00003717
WBPaper00026841
WBPaper00027263
Curator_confirmedWBPerson567
Date_last_updated05 Nov 2006 00:00:00
Automated_descriptionPredicted to enable peptidase activity. Predicted to be involved in cell-cell signaling; protein autoprocessing; and system development. Predicted to be located in cell surface; extracellular region; and plasma membrane. Expressed in hyp10; hyp6; hyp7 syncytium; hyp8; and hyp9.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC29F3.2
Corresponding_CDS_historyC29F3.2:wp12
C29F3.2:wp63
Corresponding_transcriptC29F3.2.1
Other_sequenceDviv_isotig16933
SS01151
SSC04002_1
Dviv_isotig16932
Associated_featureWBsf653445
WBsf669773
WBsf1002264
WBsf1020997
WBsf235051
WBsf235052
Experimental_infoRNAi_resultWBRNAi00011331Inferred_automaticallyRNAi_primary
WBRNAi00076987Inferred_automaticallyRNAi_primary
WBRNAi00041461Inferred_automaticallyRNAi_primary
WBRNAi00027687Inferred_automaticallyRNAi_primary
Expr_patternExpr648
Expr1012897
Expr1032965
Expr1145490
Expr2018083
Expr2036221
Drives_constructWBCnstr00012473
WBCnstr00034074
Construct_productWBCnstr00034074
Microarray_results (16)
Expression_cluster (186)
Interaction (73)
WBProcessWBbiopr:00000123
Map_infoMapVPosition7.86062Error0.005823
PositivePositive_cloneC29F3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4966
5380
5413
Pseudo_map_position
Reference (11)
RemarkC09F3.d is wrong (typo?) and .d gene has been superceded. being changed to C29F3.2 a hedghog gene.[sdm 000904]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene