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WormBase Tree Display for Gene: WBGene00006954

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Name Class

WBGene00006954SMapS_parentSequenceCHROMOSOME_V
IdentityVersion1
NameCGC_namewrt-8Person_evidenceWBPerson83
Sequence_nameC29F3.2
Molecular_nameC29F3.2
C29F3.2.1
CE29200
Other_namecm20F10Paper_evidenceWBPaper00002823
CELE_C29F3.2Accession_evidenceNDBBX284605
Public_namewrt-8
DB_infoDatabaseAceViewgene5P822
WormQTLgeneWBGene00006954
WormFluxgeneWBGene00006954
NDBlocus_tagCELE_C29F3.2
PanthergeneCAEEL|WormBase=WBGene00006954|UniProtKB=Q94130
familyPTHR46706
NCBIgene180035
RefSeqproteinNM_074404.6
SwissProtUniProtAccQ94130
TREEFAMTREEFAM_IDTF316084
UniProt_GCRPUniProtAccQ94130
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classwrt
AlleleWBVar01809198
WBVar01493077
WBVar01493078
WBVar00591479
WBVar01498664
WBVar01776965
WBVar01073181
WBVar01073182
WBVar01073183
WBVar01073184
WBVar01073185
WBVar01073186
WBVar01073187
WBVar01500160
WBVar01073188
WBVar01073189
WBVar01073190
WBVar01073191
WBVar01073192
WBVar01073193
WBVar01073194
WBVar00603008
WBVar00478823
WBVar00478824
WBVar00478825
WBVar00478826
WBVar00478827
WBVar00250570
WBVar01500212
WBVar01500213
WBVar01463392
WBVar01499299
WBVar00601202
WBVar01499316
WBVar01745047
WBVar01800343
WBVar01745048
WBVar01800344
WBVar01745049
WBVar01745050
WBVar01745051
WBVar01745052
WBVar01745053
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (25)
Paralog (24)
Structured_descriptionConcise_descriptionwrt-8 encodes a hedgehog-like protein, with (from N- to C-terminus) asignal sequence, a Wart domain, an short region of low-complexitysequence, and a Hint/Hog domain; WRT-8 is strongly expressed inhypodermal syncytia hyp6-hyp10 throughout life, and in in 12 subventralP cells and their descendants from 3-fold embryo to L2 larva stages; theHint/Hog domain is predicted to cut WRT-8 into two halves and thencovalently link cholesterol to the C-terminus of the Wart domain; theWart domain is predicted to form a cysteine-crosslinked protein involvedin intercellular signalling, and it has subtle similarity to theN-terminal Hedge domain of HEDGEHOG proteins; WRT-8 has no obviousfunction in RNAi assays.Paper_evidenceWBPaper00003717
WBPaper00026841
WBPaper00027263
Curator_confirmedWBPerson567
Date_last_updated05 Nov 2006 00:00:00
Automated_descriptionPredicted to enable peptidase activity. Predicted to be involved in cell-cell signaling; protein autoprocessing; and system development. Predicted to be located in cell surface; extracellular region; and plasma membrane. Expressed in hyp10; hyp6; hyp7 syncytium; hyp8; and hyp9.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC29F3.2
Corresponding_CDS_historyC29F3.2:wp12
C29F3.2:wp63
Corresponding_transcriptC29F3.2.1
Other_sequenceDviv_isotig16933
SS01151
SSC04002_1
Dviv_isotig16932
Associated_featureWBsf653445
WBsf669773
WBsf1002264
WBsf1020997
WBsf235051
WBsf235052
Experimental_infoRNAi_resultWBRNAi00011331Inferred_automaticallyRNAi_primary
WBRNAi00076987Inferred_automaticallyRNAi_primary
WBRNAi00041461Inferred_automaticallyRNAi_primary
WBRNAi00027687Inferred_automaticallyRNAi_primary
Expr_patternExpr648
Expr1012897
Expr1032965
Expr1145490
Expr2018083
Expr2036221
Drives_constructWBCnstr00012473
WBCnstr00034074
Construct_productWBCnstr00034074
Microarray_results (16)
Expression_cluster (186)
Interaction (73)
WBProcessWBbiopr:00000123
Map_infoMapVPosition7.86062Error0.005823
PositivePositive_cloneC29F3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4966
5380
5413
Pseudo_map_position
Reference (11)
RemarkC09F3.d is wrong (typo?) and .d gene has been superceded. being changed to C29F3.2 a hedghog gene.[sdm 000904]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene