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WormBase Tree Display for Gene: WBGene00006875

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Name Class

WBGene00006875EvidencePaper_evidenceWBPaper00005969
SMapS_parentSequenceT22C8
IdentityVersion1
NameCGC_namevab-9Person_evidenceWBPerson261
Sequence_nameT22C8.8
Molecular_nameT22C8.8
T22C8.8.1
CE32938
Other_nameCELE_T22C8.8Accession_evidenceNDBBX284602
Public_namevab-9
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classvab
Reference_alleleWBVar00144274
Allele (27)
Legacy_informatione1744 : slightly dumpy tail whip knobbed at all stages except adult male (adult male tail tip slightly swollen); variably Egl. ES3 (larvae) ME2. NA3 (e1775 e2016 : resemble e1744 slightly dumpier).
See also e1744, e1775, e2016
[C.elegansII] e1744 : slightly dumpy, tail whip knobbed at all stages except adult male (adult male tail tip slightly swollen); variably Egl. ES3 (larvae) ME2. OA2: e1775, e2016 (resemble e1744, slightly dumpier). [Hodgkin 1974]
StrainWBStrain00004468
WBStrain00007740
WBStrain00007742
WBStrain00007743
WBStrain00031259
WBStrain00031254
RNASeq_FPKM (74)
GO_annotation00013081
00013082
00013083
00013084
00013085
00013086
00013087
00013088
00013089
00114959
OrthologWBGene00053963Caenorhabditis remaneiFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00023898Caenorhabditis briggsaeFrom_analysisHillier-set
OrthoMCL
OMA
Inparanoid_8
WormBase-Compara
WBGene00158597Caenorhabditis brenneriFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00132466Caenorhabditis japonicaFrom_analysisTreeFam
Inparanoid_8
WormBase-Compara
WBGene00147993Caenorhabditis brenneriFrom_analysisTreeFam
WormBase-Compara
WBGene00193298Caenorhabditis brenneriFrom_analysisTreeFam
WormBase-Compara
WBGene00226184Brugia malayiFrom_analysisWormBase-Compara
CSP26.g7399Caenorhabditis zanzibariFrom_analysisWormBase-Compara
CSP28.g14591Caenorhabditis panamensisFrom_analysisWormBase-Compara
CSP29.g21923Caenorhabditis beceiFrom_analysisWormBase-Compara
CSP31.g16732Caenorhabditis uteleiaFrom_analysisWormBase-Compara
CSP32.g4233Caenorhabditis sulstoniFrom_analysisWormBase-Compara
CSP38.g1891Caenorhabditis quiockensisFrom_analysisWormBase-Compara
CSP39.g12890Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP39.g27596Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP40.g11461Caenorhabditis tribulationisFrom_analysisWormBase-Compara
Cang_2012_03_13_00082.g3777Caenorhabditis angariaFrom_analysisWormBase-Compara
Cni-vab-9Caenorhabditis nigoniFrom_analysisWormBase-Compara
Csp11.Scaffold629.g15076Caenorhabditis tropicalisFrom_analysisWormBase-Compara
Csp5_scaffold_07020.g37280Caenorhabditis sinicaFrom_analysisWormBase-Compara
FL83_04640Caenorhabditis latensFrom_analysisWormBase-Compara
GCK72_004898Caenorhabditis remaneiFrom_analysisWormBase-Compara
OTIPU.nOt.2.0.1.g02342Oscheius tipulaeFrom_analysisWormBase-Compara
Pan_g19336Panagrellus redivivusFrom_analysisWormBase-Compara
Sp34_20294000Caenorhabditis inopinataFrom_analysisWormBase-Compara
chrII_pilon.g5310Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00247487Onchocerca volvulusFrom_analysisWormBase-Compara
WBGene00258612Strongyloides rattiFrom_analysisWormBase-Compara
WBGene00293858Trichuris murisFrom_analysisWormBase-Compara
FB:FBgn0266409Drosophila melanogasterFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
ZFIN:ZDB-GENE-040426-2644Danio rerioFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
ZFIN:ZDB-GENE-050104-1Danio rerioFrom_analysisEnsEMBL-Compara
Hieranoid
OrthoFinder
Panther
PhylomeDB
SonicParanoid
HGNC:17637Homo sapiensFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OrthoFinder
Panther
HGNC:18515Homo sapiensFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
MGI:1929938Mus musculusFrom_analysisEnsEMBL-Compara
Hieranoid
OrthoFinder
Panther
MGI:2177570Mus musculusFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
RGD:1310294Rattus norvegicusFrom_analysisEnsEMBL-Compara
Hieranoid
OrthoFinder
Panther
RGD:1564799Rattus norvegicusFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
Structured_descriptionConcise_descriptionvab-9 encodes a claudin homolog orthologous to human brain cell membrane protein 1 (BCMP1) and Drosophila CG6982; VAB-9 colocalizes with HMP-1 to an apical layer of the adherens junctions of all epithelial cells, one layer more apically than AJM-1; vab-9 mutants have disorganized F-actin at the adherens junction, implying that VAB-9 links junctions to circumferential actin filaments; VAB-9 is also expressed in the nerve ring; VAB-9 requires the cadherin HMR-1 to localize to the cell membrane, and both alpha-catenin (HMP-1) and beta-catenin (HMP-2) to remain at the cell junction after membrane localization.Paper_evidenceWBPaper00000608
WBPaper00004961
WBPaper00005946
WBPaper00005969
WBPaper00005975
WBPaper00012856
WBPaper00012883
WBPaper00018356
Person_evidenceWBPerson261
Curator_confirmedWBPerson13481
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionInvolved in cell-cell adhesion; defense response to Gram-negative bacterium; and innate immune response. Located in cell junction. Expressed in epithelial cell; hypodermis; and nerve ring. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and mutilating palmoplantar keratoderma with periorificial keratotic plaques. Is an ortholog of human TMEM47 (transmembrane protein 47).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112011Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:17637)
DOID:0050467Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:17637)
Molecular_infoCorresponding_CDST22C8.8
Corresponding_CDS_historyT22C8.8:wp92
Corresponding_transcriptT22C8.8.1
Other_sequence (22)
Associated_feature (12)
Experimental_infoRNAi_resultWBRNAi00073283Inferred_automaticallyRNAi_primary
WBRNAi00019018Inferred_automaticallyRNAi_primary
WBRNAi00065106Inferred_automaticallyRNAi_primary
WBRNAi00092872Inferred_automaticallyRNAi_primary
WBRNAi00035805Inferred_automaticallyRNAi_primary
WBRNAi00053821Inferred_automaticallyRNAi_primary
Expr_patternExpr2609
Expr2610
Expr1021012
Expr1032915
Expr1157368
Expr2017954
Expr2036090
Drives_constructWBCnstr00000672
WBCnstr00034116
Construct_productWBCnstr00034116
AntibodyWBAntibody00000653
Microarray_results (20)
Expression_cluster (142)
Interaction (27)
Map_infoMapIIPosition0.829738Error0.001028
Well_ordered
PositiveInside_rearrmnDf63
mnDf68
mnDf69
Positive_cloneT22C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point620
626
Multi_point (13)
Pos_neg_data (17)
Reference (38)
MethodGene