WormBase Tree Display for Gene: WBGene00006852
expand all nodes | collapse all nodes | view schema
| WBGene00006852 | SMap | S_parent | Sequence | C53D6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | unc-129 | Person_evidence | WBPerson261 | |||||
| Sequence_name | C53D6.2 | ||||||||
| Molecular_name | C53D6.2 | ||||||||
| C53D6.2.1 | |||||||||
| CE24863 | |||||||||
| Other_name | CELE_C53D6.2 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | unc-129 | ||||||||
| DB_info | Database | AceView | gene | 4J768 | |||||
| WormQTL | gene | WBGene00006852 | |||||||
| WormFlux | gene | WBGene00006852 | |||||||
| NDB | locus_tag | CELE_C53D6.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006852|UniProtKB=G5EBY8 | |||||||
| family | PTHR11848 | ||||||||
| NCBI | gene | 177719 | |||||||
| RefSeq | protein | NM_069165.8 | |||||||
| SwissProt | UniProtAcc | G5EBY8 | |||||||
| TREEFAM | TREEFAM_ID | TF351794 | |||||||
| UniProt_GCRP | UniProtAcc | G5EBY8 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Allele (39) | |||||||||
| Legacy_information | [Colavita A ] uncoordinated movement, DD and VD axons grow in aberrant directions | ||||||||
| [C.elegansII] ev554: uncoordinated variable kinker; axons grow inaberrant directions; suppresses guidance defects caused by ectopic UNC-5. OA2: ev557, ev566. Cloned: cosmid rescue (C53D6). [NW] | |||||||||
| Complementation_data | [Colavita A ] complements let-54(s44) | ||||||||
| Strain (47) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00000903 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00000936 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00006570 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00021594 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | unc-129 encodes a member of the TGF-beta family of secreted growth factor signaling molecules; in C. elegans, UNC-129 functions as a guidance cue that is required for dorsalward axonal guidance as well as for proper migration of the distal tip cells of the somatic gonad; in regulating axon guidance and cell migration, UNC-129 functions by promoting UNC-5/UNC-40 signaling pathways at the expense of UNC-5 signaling pathways alone; UNC-129 is expressed in dorsal body wall muscle; UNC-129 physically interacts with UNC-5 expressed in tissue culture cells. | Paper_evidence | WBPaper00003014 | |||||
| WBPaper00003139 | |||||||||
| WBPaper00004380 | |||||||||
| WBPaper00005809 | |||||||||
| WBPaper00006490 | |||||||||
| WBPaper00032506 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 27 Jan 2009 00:00:00 | ||||||||
| Automated_description | Enables signaling receptor binding activity. Involved in several processes, including axon guidance; backward locomotion; and inductive cell migration. Predicted to be located in extracellular space. Expressed in several structures, including CAN; PDE socket cell; body wall musculature; cholinergic neurons; and terminal bulb. Is an ortholog of human GDF10 (growth differentiation factor 10). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C53D6.2 | |||||||
| Corresponding_transcript | C53D6.2.1 | ||||||||
| Other_sequence | AF029887 | ||||||||
| CBC06946_1 | |||||||||
| Associated_feature | WBsf997334 | ||||||||
| WBsf1017910 | |||||||||
| WBsf230496 | |||||||||
| WBsf230497 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00090329 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00086124 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012364 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027834 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00043098 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089794 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00075918 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090170 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090011 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (17) | |||||||||
| Drives_construct (248) | |||||||||
| Construct_product | WBCnstr00021011 | ||||||||
| WBCnstr00034123 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (177) | |||||||||
| Interaction (59) | |||||||||
| WBProcess | WBbiopr:00000025 | ||||||||
| Map_info | Map | IV | Position | 4.00146 | Error | 0.001083 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | C53D6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Negative | Negative_clone | C53B4 | |||||||
| Mapping_data | Multi_point | 3431 | |||||||
| 3432 | |||||||||
| 3433 | |||||||||
| 4064 | |||||||||
| 4065 | |||||||||
| 5048 | |||||||||
| 5684 | |||||||||
| Pos_neg_data | 8903 | ||||||||
| Reference (96) | |||||||||
| Method | Gene |
