WormBase Tree Display for Gene: WBGene00006811

WBGene00006811 SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 4
    Name: CGC_name: unc-79 Person_evidence: WBPerson261
      Sequence_name: E03A3.6
      Molecular_name: E03A3.6a
        E03A3.6a.1
        CE43495
        E03A3.6b
        CE30720
        E03A3.6b.1
        E03A3.6b.2
        E03A3.6b.3
      Other_name: CELE_E03A3.6 Accession_evidence: NDB BX284603
      Public_name: unc-79
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 16 Jul 2007 17:47:14 WBPerson1983 Event: Acquires_merge: WBGene00008466
        3 16 Jul 2007 17:49:52 WBPerson1983 Event: Acquires_merge: WBGene00007272
        4 19 Jul 2007 11:54:11 WBPerson1983 Event: Acquires_merge: WBGene00008467
      Acquires_merge: WBGene00008466
        WBGene00007272
        WBGene00008467
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: unc
    Reference_allele: WBVar00143719
    Allele: WBVar00143719 Inferred_automatically: From strain object: CB1068
          From strain object: MT2550
          From strain object: MT8186
          From strain object: MT8388
          From strain object: RW1536
          From strain object: SD184
          From strain object: SD378
          From strain object: SD415
          From strain object: SD420
          From strain object: SD939
      WBVar00143895 Inferred_automatically: From strain object: CB1291
      WBVar00145089 Inferred_automatically: From strain object: CW16
      WBVar00143713
      WBVar02147651
      WBVar00145318
      WBVar00145329
      WBVar00145330
      WBVar02125771
      WBVar00144061
      WBVar00143692
      WBVar00143693
      WBVar02147652
      WBVar00395356
      WBVar00819735
      WBVar00395357
      WBVar00819736
      WBVar00819737
      WBVar00819738
      WBVar01999548
      WBVar00819739
      WBVar00819740
      WBVar00819741
      WBVar00819742
      WBVar00819743
      WBVar00819744
      WBVar01785388
      WBVar00819745
      WBVar01785389
      WBVar00819746
      WBVar01785390
      WBVar00819747
      WBVar00819748
      WBVar00819749
      WBVar00819750
      WBVar00819751
      WBVar00819752
      WBVar00819753
      WBVar00819754
      WBVar00819755
      WBVar00819756
      WBVar00819757
      WBVar00819758
      WBVar01493467
      WBVar00819759
      WBVar02067463
      WBVar00819760
      WBVar02067464
      WBVar00819761
      WBVar00819762
      WBVar00052301
      WBVar01628425
      WBVar01628426
      WBVar01396696
      WBVar01396697
      WBVar01262721
      WBVar00264855
      WBVar01262723
      WBVar01262725
      WBVar00256583
      WBVar01656498
      WBVar01656499
      WBVar01656500
      WBVar00266158
      WBVar01656501
      WBVar01656502
      WBVar01644011
      WBVar01578845
      WBVar01578846
      WBVar01578847
      WBVar01578848
      WBVar01823275
      WBVar02144167
      WBVar00253299
      WBVar02069585
      WBVar02151518
      WBVar01962680
      WBVar00819652
      WBVar00819653
      WBVar00819654
      WBVar00819655
      WBVar00819656
      WBVar00819657
      WBVar00819658
      WBVar00819659
      WBVar01837419
      WBVar00819660
      WBVar00263808
      WBVar00819661
      WBVar00819662
      WBVar00819663
      WBVar00819664
      WBVar00563042
      WBVar00563043
      WBVar00819665
      WBVar00819666
      WBVar00819667
      WBVar00819668
      WBVar00819669
      WBVar00819670
      WBVar01445170
      WBVar00819671
      WBVar01445173
      WBVar00819672
      WBVar01445174
      WBVar00819673
      WBVar01445175
      WBVar00819674
      WBVar00819675
      WBVar00300949
      WBVar00819676
      WBVar00819677
      WBVar00819678
      WBVar00819679
      WBVar00819680
      WBVar00819681
      WBVar00058741
      WBVar00819682
      WBVar00819683
      WBVar00058746
      WBVar00819684
      WBVar00250939
      WBVar00819685
      WBVar00819686
      WBVar00819687
      WBVar00058751
      WBVar00819688
      WBVar01499654
      WBVar00819689
      WBVar00819690
      WBVar00058756
      WBVar00819691
      WBVar00819692
      WBVar00058761
      WBVar00819693
      WBVar00099208
      WBVar00253166
      WBVar00819694
      WBVar00058766
      WBVar00819695
      WBVar00819696
      WBVar00819697
      WBVar00819698
      WBVar00058771
      WBVar00819699
      WBVar00819700
      WBVar00058776
      WBVar00819701
      WBVar00819702
      WBVar01990059
      WBVar00819703
      WBVar00058781
      WBVar00819704
      WBVar00819705
      WBVar00395327
      WBVar01606995
      WBVar00819706
      WBVar00395328
      WBVar00819707
      WBVar00395329
      WBVar00058786
      WBVar00819708
      WBVar02089656
      WBVar00395330
      WBVar00395331
      WBVar00819709
      WBVar00395332
      WBVar00058791
      WBVar00819710
      WBVar00240306
      WBVar00395333
      WBVar00819711
      WBVar00395334
      WBVar00819712
      WBVar00819713
      WBVar00395335
      WBVar00058796
      WBVar00819714
      WBVar02131829
      WBVar00395336
      WBVar02131830
      WBVar00819715
      WBVar00395337
      WBVar00058801
      WBVar00819716
      WBVar02131831
      WBVar00395338
      WBVar00819717
      WBVar00395339
      WBVar00395340
      WBVar00819718
      WBVar00058806
      WBVar00819719
      WBVar00395341
      WBVar00819720
      WBVar00395342
      WBVar00819721
      WBVar00395343
      WBVar00819723
      WBVar00058811
      WBVar00395344
      WBVar00395345
      WBVar00819724
      WBVar00819725
      WBVar00395346
      WBVar00243998
      WBVar00395347
      WBVar00819726
      WBVar00819727
      WBVar00395348
      WBVar00819728
      WBVar00395349
      WBVar00395350
      WBVar00819729
      WBVar00819730
      WBVar00395351
      WBVar00819731
      WBVar00395352
      WBVar00819732
      WBVar00395353
      WBVar00819733
      WBVar00395354
      WBVar00819734
      WBVar00395355
    Legacy_information: e1068 : irregular movement somewhat sluggish. ES2 ME3. NA4 (e1031 etc.).
      See also e1030, e1031, e1068, e1291, e1510
      [C.elegansII] e1068 : irregular movement, somewhat sluggish ("fainter"); hypersensitive to volatile anaesthetics.ES2 ME3. OA>5: e1031, e1291, e1510, ec1 etc. [Sedensky and Meneely 1987; Morgan et al. 1991; CW]
    Strain (12)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (43)
    Structured_description: Concise_description: unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with unc-77 and nca-2, which encode alpha-1 subunits of voltage-insensitive cation leak channels, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of UNC-77 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults; UNC-79 exhibits a punctate staining pattern in ventral nerve cord and nerve ring processes, and this staining is dependent upon UNC-80, UNC-77, and NCA-2. Paper_evidence: WBPaper00001281
            WBPaper00030757
            WBPaper00031592
          Curator_confirmed: WBPerson1843
            WBPerson324
          Date_last_updated: 22 Jun 2010 00:00:00
      Automated_description: Involved in several processes, including response to anesthetic; response to ethanol; and response to toluene. Located in axon. Expressed in head neurons; nerve ring; nervous system; tail neurons; and ventral cord neurons. Used to study alcohol use disorder. Is an ortholog of human UNC79 (unc-79 homolog, NALCN channel complex subunit). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:1574 Homo sapiens Paper_evidence: WBPaper00002358
          Curator_confirmed: WBPerson324
          Date_last_updated: 29 Apr 2019 00:00:00
  Models_disease_in_annotation: WBDOannot00000654
  Molecular_info: Corresponding_CDS: E03A3.6a
      E03A3.6b
    Corresponding_CDS_history: E03A3.6:wp79
      E03A3.6:wp179
      E03A3.6:wp183
      E03A3.6a:wp200
    Corresponding_transcript: E03A3.6a.1
      E03A3.6b.1
      E03A3.6b.2
      E03A3.6b.3
    Other_sequence (50)
    Associated_feature (23)
  Experimental_info: RNAi_result (26)
    Expr_pattern: Expr8062
      Expr8326
      Expr16167
      Expr1027571
      Expr1032877
      Expr1147615
      Expr2017908
      Expr2036044
    Drives_construct: WBCnstr00013262
      WBCnstr00017149
      WBCnstr00042791
    Construct_product: WBCnstr00017149
    Antibody: WBAntibody00001385
      WBAntibody00002202
    Microarray_results (50)
    Expression_cluster (204)
    Interaction (66)
  Map_info: Map: III Position: -3.89038 Error: 0.022171
    Well_ordered
    Positive: Inside_rearr: nDf10
        nDf11
        nDf14
      Positive_clone: E03A3 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 60
        2714
        7066
      Multi_point (30)
      Pos_neg_data (14)
  Reference (74)
  Method: Gene