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WormBase Tree Display for Gene: WBGene00006782

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Name Class

WBGene00006782SMapS_parentSequenceC04F5
IdentityVersion2
NameCGC_nameunc-46Paper_evidenceWBPaper00000031
Sequence_nameC04F5.3
Molecular_nameC04F5.3
C04F5.3.1
CE27791
Other_nameCELE_C04F5.3Accession_evidenceNDBBX284605
Public_nameunc-46
DB_infoDatabaseAceViewgene5F576
WormQTLgeneWBGene00006782
WormFluxgeneWBGene00006782
NDBlocus_tagCELE_C04F5.3
NCBIgene178897
RefSeqproteinNM_071964.5
TREEFAMTREEFAM_IDTF320931
TrEMBLUniProtAccQ9GZD5
UniProt_GCRPUniProtAccQ9GZD5
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:42WBPerson1971EventImportedInitial conversion from geneace
223 Mar 2005 14:05:09WBPerson2970EventAcquires_mergeWBGene00015445
Acquires_mergeWBGene00015445
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classunc
Reference_alleleWBVar00143011
Allele (38)
Legacy_informatione177 : shrinker contracts both dorsally and ventrally when prodded slow good forward movement poor backing; slightly small. ES3 ME2. NA3 (e300 e642).
[C.elegansII] e177 : shrinker contracts both dorsally and ventrally when prodded, slow, good forward movement, poor backing; slightly small. ES3 ME2. OA2: e300, e642. [Brenner 1974; McIntire et al. 1993; MT]
Strain (163)
RNASeq_FPKM (74)
GO_annotation (2)
Ortholog (29)
Structured_descriptionConcise_descriptionunc-46 encodes a type I transmembrane protein that contains a single motif similar to the LAMP (lysosomal associated membrane glycoprotein) domain; UNC-46 and UNC-47, the C. elegans vesicular GABA transporter, are required in GABAergic neurons for loading GABA into synaptic vesicles and thus, for all GABA-mediated behaviors; a rescuing UNC-46::GFP fusion protein localizes to synaptic varicosities in the dorsal and ventral nerve cords; UNC-46 and UNC-47 are mutually required for sorting/localization to synaptic vesicles; when overexpressed, unc-47 can rescue unc-46 mutant animals.Paper_evidenceWBPaper00030788
Curator_confirmedWBPerson1843
Date_last_updated12 Jun 2008 00:00:00
Automated_descriptionLocated in cytoplasmic vesicle and neuromuscular junction. Expressed in GLR and neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC04F5.3
Corresponding_transcriptC04F5.3.1
Other_sequenceAcan_isotig12346
Associated_featureWBsf652609
WBsf999935
WBsf233650
Experimental_infoRNAi_resultWBRNAi00090126Inferred_automaticallyRNAi_primary
WBRNAi00039641Inferred_automaticallyRNAi_primary
WBRNAi00028449Inferred_automaticallyRNAi_primary
WBRNAi00089966Inferred_automaticallyRNAi_primary
WBRNAi00010134Inferred_automaticallyRNAi_primary
WBRNAi00089726Inferred_automaticallyRNAi_primary
WBRNAi00090284Inferred_automaticallyRNAi_primary
Expr_patternExpr4785
Expr4786
Expr13159
Expr15441
Expr1021811
Expr1143737
Expr2017879
Expr2036015
Drives_constructWBCnstr00001640
WBCnstr00008362
WBCnstr00008363
WBCnstr00012243
WBCnstr00020699
WBCnstr00034155
Construct_productWBCnstr00001640
WBCnstr00034155
WBCnstr00038183
Microarray_results (20)
Expression_cluster (116)
InteractionWBInteraction000502940
WBInteraction000502941
WBInteraction000502942
WBInteraction000518962
WBProcessWBbiopr:00000010
Map_infoMapVPosition-2.52065Error0.028521
Well_ordered
PositiveInside_rearrnDf32
yDp1
nDf33
sDf26
rT1
Positive_cloneC04F5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point (27)
Multi_point137
139
141
268
288
451
481
641
658
883
884
886
1144
1149
1184
1302
1533
1559
1560
1806
2270
2412
2415
2418
2419
2820
2821
2822
3489
3493
3495
3549
3573
3705
3794
3988
3965
4492
5455
5463
5732
Pos_neg_data845
2134
3076
3259
Reference (65)
MethodGene