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WormBase Tree Display for Gene: WBGene00006596

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Name Class

WBGene00006596SMapS_parentSequenceY56A3A
IdentityVersion1
NameCGC_nametop-3
Sequence_nameY56A3A.27
Molecular_nameY56A3A.27
Y56A3A.27.1
CE28138
Other_nameTOP3Accession_evidenceEMBLAF057032
Y56A3APaper_evidenceWBPaper00004118
CELE_Y56A3A.27Accession_evidenceNDBBX284603
Public_nametop-3
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtop
Allele (311)
Possibly_affected_byWBVar02152868
WBVar02153516
StrainWBStrain00051674
WBStrain00051660
RNASeq_FPKM (74)
GO_annotation (19)
Contained_in_operonCEOP3746
Ortholog (38)
ParalogWBGene00012995Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptiontop-3 encodes DNA topoisomerase IIIalpha.Paper_evidenceWBPaper00004118
Curator_confirmedWBPerson1843
Date_last_updated20 Jul 2006 00:00:00
Automated_descriptionEnables DNA topoisomerase type I (single strand cut, ATP-independent) activity. Involved in DNA topological change. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5. Is an ortholog of human TOP3A (DNA topoisomerase III alpha).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelEFO:MONDO:0020629Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11992)
DOID:0111524Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11992)
Molecular_infoCorresponding_CDSY56A3A.27
Corresponding_CDS_historyY56A3A.27:wp52
Corresponding_transcriptY56A3A.27.1
Other_sequence (27)
Associated_featureWBsf994542
WBsf994543
WBsf1016118
WBsf1016119
WBsf1016120
WBsf1016121
WBsf227619
Experimental_infoRNAi_result (13)
Expr_patternExpr983
Expr1011308
Expr1032729
Expr1161011
Expr2017459
Expr2035598
Microarray_results (18)
Expression_cluster (73)
Interaction (66)
Map_infoMapIIIPosition13.556Error0.030041
PositivePositive_cloneY56A3AInferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4180
4904
Pseudo_map_position
Reference (14)
RemarkY56A3A.Z cahnged to .27 following on from sequence annotation. [sdm 05/00]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene