WormBase Tree Display for Gene: WBGene00006588

WBGene00006588 SMap: S_parent: Sequence: C14F5
  Identity: Version: 2
    Name: CGC_name: tnt-3 Person_evidence: WBPerson819
      Sequence_name: C14F5.3
      Molecular_name (23)
      Other_name: esp-1 Paper_evidence: WBPaper00005370
        CELE_C14F5.3 Accession_evidence: NDB BX284606
      Public_name: tnt-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:41 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 04 Sep 2008 13:46:57 WBPerson2970 Name_change: Other_name: esp-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tnt
    Allele (155)
    Strain: WBStrain00031767
      WBStrain00035660
    RNASeq_FPKM (74)
    GO_annotation: 00003817
      00003818
      00003819
      00003820
      00114390
      00114391
    Ortholog: WBGene00051229 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00036678 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00160232 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00105403 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      WBGene00113128 Pristionchus pacificus From_analysis: OMA
      WBGene00121702 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g3949 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g12118 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g10870 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g17637 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g20520 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g21779 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g4048 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g6002 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g5731 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g8289 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00065.g3170 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-tnt-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g18910 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00251.g7976 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_00062 Caenorhabditis latens From_analysis: WormBase-Compara
      Sp34_X0213810 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g19490 Caenorhabditis elegans From_analysis: WormBase-Compara
      FB:FBgn0004169 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-041210-27 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:11948 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      HGNC:11949 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      HGNC:11950 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      MGI:1333868 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      MGI:104597 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      MGI:109550 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:3882 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:3883 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:621852 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
    Paralog: WBGene00003495 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006587 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006589 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Concise_description: tnt-3 is orthologous to the human gene TROPONIN T (TNNT2; OMIM:191045), which when mutated leads to disease. Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable tropomyosin binding activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in several diseases, including distal arthrogryposis type 2B2; intrinsic cardiomyopathy (multiple); and nemaline myopathy (multiple). Is an ortholog of human TNNT1 (troponin T1, slow skeletal type); TNNT2 (troponin T2, cardiac type); and TNNT3 (troponin T3, fast skeletal type). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (14)
  Molecular_info: Corresponding_CDS: C14F5.3a
      C14F5.3b
      C14F5.3c
      C14F5.3d
      C14F5.3e
      C14F5.3f
    Corresponding_CDS_history: C14F5.3a:wp128
      C14F5.3a:wp271
      C14F5.3b:wp128
      C14F5.3b:wp271
      C14F5.3c:wp128
      C14F5.3d:wp271
    Corresponding_transcript (11)
    Other_sequence (32)
    Associated_feature: WBsf654174
      WBsf655679
      WBsf670786
      WBsf718634
      WBsf718635
      WBsf1005991
      WBsf1005992
      WBsf1023332
      WBsf237626
      WBsf237627
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr1023347
      Expr1032721
      Expr1144619
      Expr2017436
      Expr2035575
    Drives_construct: WBCnstr00034285
    Construct_product: WBCnstr00034285
    Microarray_results (38)
    Expression_cluster (176)
    Interaction (32)
  Map_info: Map: X Position: -0.881659 Error: 0.023935
    Positive: Positive_clone: C14F5 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4730
    Pseudo_map_position
  Reference (12)
  Remark: Sequence connection from [Bucher EA]. 02/06/12 krb.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene