WormBase Tree Display for Gene: WBGene00006544

WBGene00006544 SMap: S_parent: Sequence: ZK328
  Identity: Version: 1
    Name: CGC_name: tbx-7
      Sequence_name: ZK328.8
      Molecular_name: ZK328.8a
        ZK328.8a.1
        CE50285
        ZK328.8b
        CE50302
        ZK328.8b.1
      Other_name: CELE_ZK328.8 Accession_evidence: NDB BX284603
      Public_name: tbx-7
    DB_info: Database: AceView gene 3H114
        WormQTL gene WBGene00006544
        WormFlux gene WBGene00006544
        NDB locus_tag CELE_ZK328.8
        Panther gene CAEEL|WormBase=WBGene00006544|UniProtKB=Q95PX3
          family PTHR11267
        NCBI gene 260030
        RefSeq protein NM_001379739.1
            NM_001379738.1
        SwissProt UniProtAcc Q95PX3
        UniProt_GCRP UniProtAcc Q95PX3
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:41 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tbx
    Allele (44)
    Legacy_information: [C.elegansII] NMK. Similarity to mouse Tbx genes. (ZK328) [Agulnik et al. 1995]
    Strain: WBStrain00036949
      WBStrain00037004
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (29)
    Paralog (20)
    Structured_description: Concise_description: tbx-7 encodes one of 21 C. elegans T-box transcription factors; in large-scale RNAi screens for early embryonic defects, loss of tbx-7 activity results in no obvious abnormalities; thus, the precise role of tbx-7 in C. elegans development and/or behavior is not yet known. Paper_evidence: WBPaper00002132
            WBPaper00002863
            WBPaper00024194
            WBPaper00025054
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 05 Oct 2005 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK328.8a
      ZK328.8b
    Corresponding_CDS_history: ZK328.8:wp245
    Corresponding_transcript: ZK328.8a.1
      ZK328.8b.1
    Associated_feature: WBsf666950
      WBsf666951
      WBsf666952
      WBsf226752
    Transcription_factor: WBTranscriptionFactor000209
  Experimental_info: RNAi_result: WBRNAi00059344 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014087
      Expr1162771
      Expr1200094
      Expr2017358
      Expr2035495
    Drives_construct: WBCnstr00034309
    Construct_product: WBCnstr00021745
      WBCnstr00034309
    Microarray_results (19)
    Expression_cluster: WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045257:bar-1(ga80)_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00045918:96h_infection_recovery_upregulated
      WBPaper00049377:MWCNT_upregulated
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050903:mir-35-41(nDf50)_25C_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056330:glycine_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060445:ikb-1(nr2027)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_downregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061040:FW1256_downregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AVA
      WBPaper00061340:GLR
      WBPaper00061340:M1_parent
      WBPaper00061340:Pharyngeal_neuron
      WBPaper00061340:pm3_pm4_pm5
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb131_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:dsh-1_3575-C40A11.4
      WBPaper00061753:csr-1(tor159)_upregulated_20C
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062335:sir-2.1(ok434)_downregulated_L3
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00064999:miR-229-64-65-66_upregulated
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00025032:cluster_37
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_E
      WBPaper00038172:aak-2overexpression_down_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00048567:dnj-14_downregulated
      WBPaper00048989:N2_allantoin_upregulated
      [cgc5767]:cluster_12
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(143_min)
      [cgc5767]:expression_class_SE
      [cgc5767]:expression_class_SE_pi(143_min)
  Map_info: Map: III Position: -1.42567 Error: 0.000525
    Positive: Positive_clone: ZK328 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4248
    Pseudo_map_position
  Reference: WBPaper00002132
    WBPaper00002863
    WBPaper00024194
    WBPaper00027309
    WBPaper00028546
    WBPaper00038491
    WBPaper00055090
    WBPaper00061738
    WBPaper00064942
  Remark: Sequence connection updated to .8 from .6 as the original .6 gene prediction has been split into two. [krb 030411]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene