WormBase Tree Display for Gene: WBGene00006496
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WBGene00006496 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 6 | |||||||
Name | CGC_name | cgef-1 | Person_evidence | WBPerson3190 | |||||
Sequence_name | C14A11.3 | ||||||||
Molecular_name | C14A11.3a | ||||||||
C14A11.3a.1 | |||||||||
CE08151 | |||||||||
C14A11.3b | |||||||||
CE47800 | |||||||||
C14A11.3c | |||||||||
CE41760 | |||||||||
C14A11.3b.1 | |||||||||
C14A11.3c.1 | |||||||||
Other_name | tag-150 | Person_evidence | WBPerson201 | ||||||
CELE_C14A11.3 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | cgef-1 | ||||||||
DB_info | Database | AceView | gene | XD417 | |||||
WormQTL | gene | WBGene00006496 | |||||||
WormFlux | gene | WBGene00006496 | |||||||
NDB | locus_tag | CELE_C14A11.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00006496|UniProtKB=H2KYI7 | |||||||
family | PTHR22826 | ||||||||
NCBI | gene | 180571 | |||||||
RefSeq | protein | NM_171641.6 | |||||||
NM_001129633.5 | |||||||||
NM_171642.7 | |||||||||
TREEFAM | TREEFAM_ID | TF332360 | |||||||
TrEMBL | UniProtAcc | H2KYI7 | |||||||
H2KYI8 | |||||||||
O02134 | |||||||||
UniProt_GCRP | UniProtAcc | H2KYI7 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 28 May 2004 13:57:59 | WBPerson1971 | Event | Acquires_merge | WBGene00015749 | ||||
3 | 18 Jul 2008 10:54:16 | WBPerson2970 | Name_change | CGC_name | cgef-1 | ||||
Other_name | tag-150 | ||||||||
4 | 13 Aug 2012 10:31:28 | WBPerson1849 | Event | Acquires_merge | WBGene00194671 | ||||
5 | 13 Aug 2012 10:31:28 | WBPerson1849 | Event | Acquires_merge | WBGene00018887 | ||||
6 | 13 Aug 2012 10:31:28 | WBPerson1849 | Event | Acquires_merge | WBGene00018889 | ||||
Acquires_merge | WBGene00015749 | ||||||||
WBGene00194671 | |||||||||
WBGene00018887 | |||||||||
WBGene00018889 | |||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cgef | ||||||||
Allele (410) | |||||||||
Strain | WBStrain00035827 | ||||||||
WBStrain00040403 | |||||||||
WBStrain00040404 | |||||||||
WBStrain00040405 | |||||||||
WBStrain00040406 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00021671 | ||||||||
00021672 | |||||||||
00021673 | |||||||||
00021674 | |||||||||
00021675 | |||||||||
00021676 | |||||||||
00114153 | |||||||||
Ortholog (66) | |||||||||
Paralog | WBGene00006805 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00022391 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WBGene00015704 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WormBase-Compara | |||||||||
WBGene00006887 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00009337 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00010111 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00010776 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | cgef-1 encodes a putative guanine nucleotide exchange factor (GEF) and positively regulates CDC-42 during asymmetric division in the embryo; cgef-1 also affects the localization of PAR proteins in the embryo; since cgef-1 mutants exhibit mild phenotypes, cgef-1 may function redundantly with other GEFs to regulate CDC-42 function; CGEF-1 expressed under germline regulatory control is enriched in the nucleoplasm and cell cortex and localizes to the cytoplasm. | Paper_evidence | WBPaper00035488 | |||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 04 Apr 2011 00:00:00 | ||||||||
Automated_description | Predicted to enable guanyl-nucleotide exchange factor activity. Involved in protein localization. Located in cell cortex and nucleoplasm. Expressed in hermaphrodite gonad; neurons; somatic gonad precursor; and vulva. Is an ortholog of human MCF2 (MCF.2 cell line derived transforming sequence); MCF2L (MCF.2 cell line derived transforming sequence like); and MCF2L2 (MCF.2 cell line derived transforming sequence-like 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C14A11.3a | |||||||
C14A11.3b | |||||||||
C14A11.3c | |||||||||
Corresponding_CDS_history | C14A11.3b:wp233 | ||||||||
Corresponding_transcript | C14A11.3a.1 | ||||||||
C14A11.3b.1 | |||||||||
C14A11.3c.1 | |||||||||
Other_sequence (12) | |||||||||
Associated_feature (29) | |||||||||
Experimental_info | RNAi_result | WBRNAi00048514 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00048515 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00086072 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00040462 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00010705 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00048512 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00028854 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00010704 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00015737 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00040461 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (13) | |||||||||
Drives_construct | WBCnstr00005760 | ||||||||
WBCnstr00005761 | |||||||||
WBCnstr00037894 | |||||||||
WBCnstr00039961 | |||||||||
WBCnstr00039962 | |||||||||
Construct_product | WBCnstr00013572 | ||||||||
WBCnstr00017411 | |||||||||
WBCnstr00037894 | |||||||||
Antibody | WBAntibody00002109 | ||||||||
Microarray_results (65) | |||||||||
Expression_cluster (179) | |||||||||
Interaction | WBInteraction000427331 | ||||||||
WBInteraction000504195 | |||||||||
WBInteraction000504198 | |||||||||
WBInteraction000504199 | |||||||||
WBInteraction000504200 | |||||||||
WBInteraction000519968 | |||||||||
WBInteraction000551256 | |||||||||
WBInteraction000556753 | |||||||||
Map_info | Map | X | Position | -13.036 | Error | 0.227099 | |||
Positive | Positive_clone | C14A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4942 | |||||||
Pseudo_map_position | |||||||||
Reference (15) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |