WormBase Tree Display for Gene: WBGene00006414
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| WBGene00006414 | SMap | S_parent | Sequence | T24F1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | raga-1 | Person_evidence | WBPerson4055 | |||||
| Sequence_name | T24F1.1 | ||||||||
| Molecular_name | T24F1.1 | ||||||||
| T24F1.1.1 | |||||||||
| CE02361 | |||||||||
| Other_name | tag-29 | Person_evidence | WBPerson201 | ||||||
| CELE_T24F1.1 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | raga-1 | ||||||||
| DB_info | Database | AceView | gene | 2L593 | |||||
| WormQTL | gene | WBGene00006414 | |||||||
| WormFlux | gene | WBGene00006414 | |||||||
| NDB | locus_tag | CELE_T24F1.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006414|UniProtKB=Q22743 | |||||||
| family | PTHR11259 | ||||||||
| NCBI | gene | 174726 | |||||||
| RefSeq | protein | NM_001393190.1 | |||||||
| TREEFAM | TREEFAM_ID | TF300616 | |||||||
| TrEMBL | UniProtAcc | Q22743 | |||||||
| UniProt_GCRP | UniProtAcc | Q22743 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 14 May 2004 16:27:42 | WBPerson1845 | Event | Acquires_merge | WBGene00006502 | ||||
| 3 | 20 Jul 2007 11:50:19 | WBPerson2970 | Name_change | CGC_name | raga-1 | ||||
| Other_name | tag-29 | ||||||||
| Acquires_merge | WBGene00006502 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | raga | ||||||||
| Allele (20) | |||||||||
| Strain | WBStrain00035594 | ||||||||
| WBStrain00035849 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Contained_in_operon | CEOP2528 | ||||||||
| Ortholog (40) | |||||||||
| Paralog | WBGene00012497 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | raga-1 encodes the C. elegans ortholog of the ras-related GTPase RagA; in C. elegans RAGA-1 functions as a modifier of behavioral aging and adult lifespan (particularly under high food concentration); raga-1 mutations also affect body size and reproduction; genetic analyses suggest that raga-1 functions in the let-363/Tor pathway to regulate behavioral aging and lifespan and also interacts with the daf-2/daf-16 insulin signaling pathway and skn-1; raga-1 reporter fusions are widely expressed in larvae, with more restricted expression (gut, head and tail neurons, somatic gonad, hypodermis) seen in adults. | Paper_evidence | WBPaper00036348 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 18 Aug 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTPase activity. Involved in several processes, including determination of adult lifespan; positive regulation of TOR signaling; and regulation of growth. Predicted to be located in lysosome and nucleus. Predicted to be part of Gtr1-Gtr2 GTPase complex. Expressed in several structures, including anterior hypodermis and gonad. Is an ortholog of human RRAGA (Ras related GTP binding A). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T24F1.1 | |||||||
| Corresponding_transcript | T24F1.1.1 | ||||||||
| Other_sequence (37) | |||||||||
| Associated_feature | WBsf222121 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00054072 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00035931 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00019167 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061894 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr15312 | ||||||||
| Expr15879 | |||||||||
| Expr15880 | |||||||||
| Expr1010332 | |||||||||
| Expr1032603 | |||||||||
| Expr1157616 | |||||||||
| Expr2015245 | |||||||||
| Expr2033479 | |||||||||
| Drives_construct | WBCnstr00006963 | ||||||||
| WBCnstr00006964 | |||||||||
| WBCnstr00034365 | |||||||||
| WBCnstr00042573 | |||||||||
| WBCnstr00042574 | |||||||||
| Construct_product (25) | |||||||||
| Regulate_expr_cluster | WBPaper00057196:raga-1(ok386)_downregulated) | ||||||||
| WBPaper00057196:raga-1(ok386)_upregulated) | |||||||||
| WBPaper00066005:RAGA-1_degradation_neuronal_downregulated | |||||||||
| WBPaper00066005:RAGA-1_degradation_neuronal_upregulated | |||||||||
| WBPaper00066005:RAGA-1_degradation_somatic_downregulated | |||||||||
| WBPaper00066005:RAGA-1_degradation_somatic_upregulated | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (96) | |||||||||
| Interaction (67) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | II | Position | 3.40657 | Error | 0.003047 | |||
| Positive | Positive_clone | T24F1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5535 | |||||||
| Pseudo_map_position | |||||||||
| Reference (29) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
