WormBase Tree Display for Gene: WBGene00006381
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| WBGene00006381 | SMap | S_parent | Sequence | Y54E2A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | tac-1 | Person_evidence | WBPerson208 | |||||
| Sequence_name | Y54E2A.3 | ||||||||
| Molecular_name | Y54E2A.3 | ||||||||
| Y54E2A.3.1 | |||||||||
| CE20302 | |||||||||
| Other_name | 2P40 | Accession_evidence | EMBL | AF326937 | |||||
| CELE_Y54E2A.3 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | tac-1 | ||||||||
| DB_info | Database | AceView | gene | 2P38 | |||||
| WormQTL | gene | WBGene00006381 | |||||||
| WormFlux | gene | WBGene00006381 | |||||||
| NDB | locus_tag | CELE_Y54E2A.3 | |||||||
| NCBI | gene | 175133 | |||||||
| RefSeq | protein | NM_064658.8 | |||||||
| SwissProt | UniProtAcc | G5ECG0 | |||||||
| UniProt_GCRP | UniProtAcc | G5ECG0 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tac | ||||||||
| Allele (20) | |||||||||
| Strain | WBStrain00037424 | ||||||||
| WBStrain00007335 | |||||||||
| WBStrain00007333 | |||||||||
| WBStrain00050672 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (46) | |||||||||
| Contained_in_operon | CEOP2648 | ||||||||
| Ortholog (20) | |||||||||
| Structured_description | Concise_description | tac-1 encodes the sole C. elegans member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; during early embryogenesis, TAC-1 activity is essential for such microtubule-based processes as pronuclear migration and mitotic spindle elongation; TAC-1 interacts in vivo with, and mutually stabilizes, ZYG-9, a microtubule-associated protein (MAP) also required for pronuclear migration; TAC-1 also interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 is a core component of centrosomes, and also localizes to the meiotic spindle poles, the mitotic spindle, and the cytoplasm. | Paper_evidence | WBPaper00006059 | |||||
| WBPaper00006060 | |||||||||
| WBPaper00006061 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Mar 2006 00:00:00 | ||||||||
| Automated_description | Enables protein domain specific binding activity. Involved in several processes, including regulation of microtubule polymerization or depolymerization; sexual reproduction; and spindle organization. Located in cytoplasm; kinetochore; and microtubule cytoskeleton. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y54E2A.3 | |||||||
| Corresponding_transcript | Y54E2A.3.1 | ||||||||
| Other_sequence | AF326937 | ||||||||
| FG620567.1 | |||||||||
| Associated_feature | WBsf650765 | ||||||||
| WBsf224306 | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Expr2681 | ||||||||
| Expr2683 | |||||||||
| Expr2684 | |||||||||
| Expr2685 | |||||||||
| Expr12439 | |||||||||
| Expr1020108 | |||||||||
| Expr1032578 | |||||||||
| Expr1160809 | |||||||||
| Expr2017202 | |||||||||
| Expr2035338 | |||||||||
| Construct_product | WBCnstr00005024 | ||||||||
| WBCnstr00010900 | |||||||||
| WBCnstr00015616 | |||||||||
| WBCnstr00015617 | |||||||||
| WBCnstr00020876 | |||||||||
| WBCnstr00021102 | |||||||||
| WBCnstr00022253 | |||||||||
| WBCnstr00022255 | |||||||||
| WBCnstr00022258 | |||||||||
| WBCnstr00040176 | |||||||||
| Antibody | WBAntibody00000668 | ||||||||
| WBAntibody00000669 | |||||||||
| WBAntibody00000670 | |||||||||
| WBAntibody00002182 | |||||||||
| WBAntibody00002963 | |||||||||
| WBAntibody00003043 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (114) | |||||||||
| Interaction (152) | |||||||||
| Map_info | Map | II | Position | 23.4578 | Error | 0.010609 | |||
| Positive | Positive_clone | Y54E2A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (35) | |||||||||
| Remark | Sequence connection from [Bellanger J-M, Gonczy P], 02/06/10 krb | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
