WormBase Tree Display for Gene: WBGene00006363
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WBGene00006363 | Evidence | Paper_evidence | WBPaper00005543 | |||
---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F35D2 | |||
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | syd | |||||
Allele (120) | ||||||
Strain | WBStrain00032087 | |||||
WBStrain00037967 | ||||||
WBStrain00005369 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (23) | ||||||
Ortholog (39) | ||||||
Paralog | WBGene00015267 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||
Structured_description | Concise_description | syd-1 encodes a protein that contains a Rho-GTPase-like activating domain as well as PDZ and C2 domains; during neuronal development, SYD-1 is required cell autonomously to positively regulate synaptogenesis; in regulating synapse development, SYD-1 functions as a positive regulator of SYD-2/liprin through direct interaction with ELKS-1, a pre-synaptic protein also required for synapse development; in turn, SYD-1 activity is regulated by RSY-1, a negative regulator of synaptogenesis, with which it also interacts physically; SYD-1 is expressed in neurons and localizes to presynaptic regions. | Paper_evidence | WBPaper00005543 | ||
WBPaper00028808 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 08 Mar 2010 00:00:00 | |||||
Automated_description | Enables GTPase activator activity; Roundabout binding activity; and small GTPase binding activity. Involved in cell projection organization; cellular localization; and locomotion. Located in presynaptic membrane. Expressed in nerve ring and neurons. Is an ortholog of human SYDE2 (synapse defective Rho GTPase homolog 2). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | F35D2.5a | ||||
F35D2.5c | ||||||
Corresponding_CDS_history | F35D2.5:wp84 | |||||
F35D2.5:wp92 | ||||||
F35D2.5b:wp93 | ||||||
F35D2.5b:wp274 | ||||||
Corresponding_transcript | F35D2.5a.1 | |||||
F35D2.5c.1 | ||||||
F35D2.5c.2 | ||||||
Other_sequence (15) | ||||||
Associated_feature (15) | ||||||
Experimental_info | RNAi_result | WBRNAi00082910 | Inferred_automatically | RNAi_primary | ||
WBRNAi00046330 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00031774 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00014326 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern (11) | ||||||
Drives_construct | WBCnstr00000711 | |||||
WBCnstr00000728 | ||||||
WBCnstr00010752 | ||||||
WBCnstr00034391 | ||||||
Construct_product | WBCnstr00000728 | |||||
WBCnstr00007017 | ||||||
WBCnstr00010752 | ||||||
WBCnstr00010753 | ||||||
WBCnstr00012368 | ||||||
WBCnstr00012375 | ||||||
WBCnstr00018295 | ||||||
WBCnstr00021865 | ||||||
WBCnstr00034391 | ||||||
WBCnstr00038079 | ||||||
Antibody | WBAntibody00000569 | |||||
Microarray_results (33) | ||||||
Expression_cluster (201) | ||||||
Interaction (51) | ||||||
Map_info (4) | ||||||
Reference (52) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |