WormBase Tree Display for Gene: WBGene00006363
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WBGene00006363 | Evidence | Paper_evidence | WBPaper00005543 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F35D2 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | syd | ||||||
Allele (120) | |||||||
Strain | WBStrain00032087 | ||||||
WBStrain00037967 | |||||||
WBStrain00005369 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (23) | |||||||
Ortholog (39) | |||||||
Paralog | WBGene00015267 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
Structured_description | Concise_description | syd-1 encodes a protein that contains a Rho-GTPase-like activating domain as well as PDZ and C2 domains; during neuronal development, SYD-1 is required cell autonomously to positively regulate synaptogenesis; in regulating synapse development, SYD-1 functions as a positive regulator of SYD-2/liprin through direct interaction with ELKS-1, a pre-synaptic protein also required for synapse development; in turn, SYD-1 activity is regulated by RSY-1, a negative regulator of synaptogenesis, with which it also interacts physically; SYD-1 is expressed in neurons and localizes to presynaptic regions. | Paper_evidence | WBPaper00005543 | |||
WBPaper00028808 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 08 Mar 2010 00:00:00 | ||||||
Automated_description | Enables GTPase activator activity; Roundabout binding activity; and small GTPase binding activity. Involved in cell projection organization; cellular localization; and locomotion. Located in presynaptic membrane. Expressed in nerve ring and neurons. Is an ortholog of human SYDE2 (synapse defective Rho GTPase homolog 2). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F35D2.5a | |||||
F35D2.5c | |||||||
Corresponding_CDS_history | F35D2.5:wp84 | ||||||
F35D2.5:wp92 | |||||||
F35D2.5b:wp93 | |||||||
F35D2.5b:wp274 | |||||||
Corresponding_transcript | F35D2.5a.1 | ||||||
F35D2.5c.1 | |||||||
F35D2.5c.2 | |||||||
Other_sequence (15) | |||||||
Associated_feature (15) | |||||||
Experimental_info | RNAi_result | WBRNAi00082910 | Inferred_automatically | RNAi_primary | |||
WBRNAi00046330 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00031774 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00014326 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (11) | |||||||
Drives_construct | WBCnstr00000711 | ||||||
WBCnstr00000728 | |||||||
WBCnstr00010752 | |||||||
WBCnstr00034391 | |||||||
Construct_product (10) | |||||||
Antibody | WBAntibody00000569 | ||||||
Microarray_results (33) | |||||||
Expression_cluster (201) | |||||||
Interaction (51) | |||||||
Map_info | Map | II | Position | 0.504817 | Error | 4.2e-05 | |
Positive | Positive_clone | F35D2 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4188 | |||||
4715 | |||||||
4733 | |||||||
5534 | |||||||
Pseudo_map_position | |||||||
Reference (52) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |