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WormBase Tree Display for Gene: WBGene00004986

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Name Class

WBGene00004986SMapS_parentSequenceT07C4
IdentityVersion1
NameCGC_namespp-1
Sequence_nameT07C4.4
Molecular_nameT07C4.4
T07C4.4.1
CE35363
Other_nameCELE_T07C4.4Accession_evidenceNDBBX284603
Public_namespp-1
DB_infoDatabaseAceViewgene3L444
WormQTLgeneWBGene00004986
WormFluxgeneWBGene00004986
NDBlocus_tagCELE_T07C4.4
NCBIgene176452
RefSeqproteinNM_066889.8
TREEFAMTREEFAM_IDTF322432
TrEMBLUniProtAccQ22291
UniProt_GCRPUniProtAccQ22291
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:37WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classspp
AlleleWBVar01500260
WBVar01499545
WBVar00407186
WBVar01499774
WBVar02019092
WBVar00093807
WBVar00252252
WBVar00855993
StrainWBStrain00032729
RNASeq_FPKM (74)
GO_annotation (14)
Contained_in_operonCEOP3839
Ortholog (22)
ParalogWBGene00004997Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
WormBase-Compara
Structured_descriptionConcise_descriptionspp-1 encodes a caenopore, a saposin (B) domain-containing protein that is a member of the saposin-like protein (SAPLIP) superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapore-like proteins; SPP-1 exhibits antibacterial activity in vitro and its expression in vivo is regulated by the DAF-2/insulin receptor signaling pathway and by the presence of bacterial pathogens such as Salmonella typhimurium and Pseudomonas aeruginosa; an spp-1::gfp reporter fusion is expressed in the intestine.Paper_evidenceWBPaper00003435
WBPaper00005976
WBPaper00029438
WBPaper00031463
WBPaper00032276
WBPaper00035289
WBPaper00041035
Curator_confirmedWBPerson1843
Date_last_updated05 Jul 2012 00:00:00
Automated_descriptionEnables pore-forming activity. Involved in defense response to other organism and pore formation in membrane of another organism. Part of pore complex.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST07C4.4
Corresponding_CDS_historyT07C4.4:wp108
Corresponding_transcriptT07C4.4.1
Other_sequenceCR10745
CBC10698_1
CRC07559_1
Associated_featureWBsf227443
Experimental_infoRNAi_result (34)
Expr_patternExpr4718
Expr8002
Expr1020872
Expr1032482
Expr1156337
Expr2016075
Expr2034311
Drives_constructWBCnstr00012195
WBCnstr00035291
Construct_productWBCnstr00012195
WBCnstr00035291
Microarray_results (25)
Expression_cluster (247)
Interaction (20)
WBProcessWBbiopr:00000008
WBbiopr:00000039
Map_infoMapIIIPosition2.4671Error0.002388
PositivePositive_cloneT07C4Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (34)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene