WormBase Tree Display for Gene: WBGene00004816

WBGene00004816 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: Y105C5B
  Identity: Version: 1
    Name: CGC_name: skr-10 Person_evidence: WBPerson322
      Sequence_name: Y105C5B.13
      Molecular_name: Y105C5B.13
        Y105C5B.13.1
        CE24062
      Other_name: CELE_Y105C5B.13 Accession_evidence: NDB BX284604
      Public_name: skr-10
    DB_info: Database: AceView gene 4Q711
        WormQTL gene WBGene00004816
        WormFlux gene WBGene00004816
        NDB locus_tag CELE_Y105C5B.13
        Panther gene CAEEL|WormBase=WBGene00004816|UniProtKB=G5EG39
          family PTHR11165
        NCBI gene 178447
        RefSeq protein NM_070501.7
        TREEFAM TREEFAM_ID TF300142
        TrEMBL UniProtAcc G5EG39
        UniProt_GCRP UniProtAcc G5EG39
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: skr
    Allele (25)
    Strain: WBStrain00037634
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (117)
    Paralog (21)
    Structured_description: Concise_description: skr-10 encodes a homolog of Skp1 in S. cerevisiae, a core component of the SCF (Skp1p, Cullin, F-box) ubiquitin-ligase complex that facilitates ubiquitin-mediated protein degradation; SKR-10 is required for posterior body morphogenesis, embryonic and larval development, and cell proliferation; SKR-10 is expressed in the tip and end regions of the intestine and can interact in vivo with CUL-1 and CUL-2, C. elegans cullin homologs. Paper_evidence: WBPaper00005128
            WBPaper00005129
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cullin family protein binding activity. Involved in embryo development; larval development; and post-embryonic body morphogenesis. Acts upstream of or within with a positive effect on mitotic cell cycle. Part of SCF ubiquitin ligase complex. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y105C5B.13
    Corresponding_transcript: Y105C5B.13.1
    Other_sequence: AF440512
      CBC02707_1
    Associated_feature: WBsf655004
      WBsf655066
      WBsf998799
      WBsf1018823
      WBsf229584
  Experimental_info: RNAi_result (13)
    Expr_pattern: Expr2444
      Expr1032392
      Expr1158726
      Expr2015838
      Expr2034071
    Drives_construct: WBCnstr00010835
      WBCnstr00035367
    Construct_product: WBCnstr00010835
      WBCnstr00035367
    Microarray_results (15)
    Expression_cluster (196)
    Interaction (25)
  Map_info: Map: IV Position: 14.4887 Error: 0.000628
    Positive: Positive_clone: Y105C5B Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005129
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene