WormBase Tree Display for Gene: WBGene00004815

WBGene00004815 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: C52D10
  Identity: Version: 1
    Name: CGC_name: skr-9 Person_evidence: WBPerson322
      Sequence_name: C52D10.7
      Molecular_name: C52D10.7
        C52D10.7.1
        CE17591
      Other_name: CELE_C52D10.7 Accession_evidence: NDB BX284604
      Public_name: skr-9
    DB_info: Database: AceView gene 4S107
        WormQTL gene WBGene00004815
        WormFlux gene WBGene00004815
        NDB locus_tag CELE_C52D10.7
        Panther gene CAEEL|WormBase=WBGene00004815|UniProtKB=G5EFA9
          family PTHR11165
        NCBI gene 178494
        RefSeq protein NM_070642.6
        TREEFAM TREEFAM_ID TF300142
        TrEMBL UniProtAcc G5EFA9
        UniProt_GCRP UniProtAcc G5EFA9
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: skr
    Allele (22)
    Strain: WBStrain00033168
    RNASeq_FPKM (74)
    GO_annotation: 00017764
      00017765
      00017766
      00017767
      00017768
      00113222
    Ortholog (116)
    Paralog (20)
    Structured_description: Concise_description: skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation. Paper_evidence: WBPaper00005128
            WBPaper00005129
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C52D10.7
    Corresponding_transcript: C52D10.7.1
    Associated_feature: WBsf998986
  Experimental_info: RNAi_result (23)
    Expr_pattern: Expr2443
      Expr1022666
      Expr1032391
      Expr1146990
      Expr2015856
      Expr2034089
    Drives_construct: WBCnstr00010834
      WBCnstr00035368
    Construct_product: WBCnstr00010834
      WBCnstr00016600
      WBCnstr00035368
    Microarray_results (16)
    Expression_cluster: WBPaper00035197:fer-1_upregulated
      WBPaper00037950:BAG-neuron_embryo_enriched
      WBPaper00037950:dopaminergic-neurons_embryo_enriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00038438:E.faecalis_24hr_downregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00040285:H2S_12hr_upregulated
      WBPaper00040285:H2S_24hr_upregulated
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00045140:aging_dynamic_regulation
      WBPaper00045618:puf-8_downregulated
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00048926:miaserin_upregulated_adult-day10
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00050370:mys-1(RNAi)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053318:Aging_upregulated_mRNA_N2
      WBPaper00053664:ins-11(tm1053)_upregulated
      WBPaper00053888:drh-3(rrr2)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055386:eat-2(ad465)_downregulated
      WBPaper00055482:Tunicamycin_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056039:hda-6(ok3203)_downregulated
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056167:Cry5B_upregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056446:hsb-1(cg116)_upregulated
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00058598:mex-1(or286)_downregulated
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_upregulated
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059224:tph-1(mg280)_upregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059373:stt-3(RNAi)_upregulated
      WBPaper00059477:hlh-2(RNAi)_regulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059728:5ug_cholesterol_downregulated
      WBPaper00059728:20ug_cholesterol_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060764:swsn-1(os22ts)_downregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061007:X.citri_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061340:Parent_of_tail_spike_and_hyp10
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_downregulated
      WBPaper00061527:fbxc-28-sdz-28
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
      WBPaper00061613:human-amyloid-beta_upregulated
      WBPaper00062156:jmjd-5(zr1234)_updownregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:daf-16(RNAi)_downregulated
      WBPaper00062456:doxycycline_downregulated_CB4856_transcript
      WBPaper00062456:doxycycline_downregulated_N2_transcript
      WBPaper00064156:lbp-3(overexpress)_downregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064505:tamoxifen_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day1_25C
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_25C
      WBPaper00065315:mating_upregulated_Day2-7
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065581:hpk-1(pk1393)_downregulated
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065835:Day5_vs_Day1_upregulated
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:Cisplatin_downregulated_diploid
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      WBPaper00066204:CdCl2_downregulated_mRNA
      WBPaper00066232:hsf-1(RNAi)_downregulated_WT
      cgc4386_cluster_6_2
      cgc4489_group_14
      WBPaper00025032:cluster_9
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027111:rrf-3(pk1426)_upregulated
      WBPaper00029437:rde-4_downregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00034739:N2lessDR1350
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00037695:LD_DD_6-day
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00039866:ClassComp_daf-19_upregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041960:kgb-1_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042258:DA1877_downregulated_GravidAdult
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00046083:oga-1(ok1207)_OP50_upregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_upregulated
      WBPaper00046083:pmk-1(km25)_OP50_upregulated
      WBPaper00048567:dnj-14_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00050767:Octopamine_induced
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_downregulated_AdultDay2
      WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:cluster_7
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(83_min)
      [cgc5767]:expression_class_E_pi(PC32)
      [cgc5767]:expression_class_SE
      [cgc5767]:expression_class_SET
      [cgc5767]:expression_class_SE_pi(PC32)
      [cgc5976]:class_2
      [cgc6390]:Cluster_E
      [cgc6390]:intrinsic
    Interaction (146)
  Map_info: Map: IV Position: 16.2315 Error: 0.000412
    Positive: Positive_clone: C52D10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005129
    WBPaper00029151
    WBPaper00033115
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene