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WormBase Tree Display for Gene: WBGene00004806

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Name Class

WBGene00004806SMapS_parentSequenceT27F2
IdentityVersion1
NameCGC_nameskp-1Person_evidenceWBPerson344
Sequence_nameT27F2.1
Molecular_nameT27F2.1
T27F2.1.1
CE06519
Other_nameCELE_T27F2.1Accession_evidenceNDBBX284605
Public_nameskp-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:36WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classskp
Allele (70)
StrainWBStrain00032959
WBStrain00037077
WBStrain00037471
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP5296
Ortholog (40)
Structured_descriptionConcise_descriptionskp-1 encodes the C. elegans ortholog of the SKI-binding protein (SKIP); skp-1 is predicted to function as a transcriptional cofactor and its activity is essential for embryogenesis and molting; skp-1 is also required for normal expression of several embryonic genes, as assayed by gfp reporter fusions; SKP-1 is widely expressed from embryogenesis through adulthood.Paper_evidenceWBPaper00005345
WBPaper00026763
Curator_confirmedWBPerson1843
Date_last_updated16 Mar 2007 00:00:00
Automated_descriptionInvolved in several processes, including molting cycle; reproductive process; and vulval development. Predicted to be part of spliceosomal complex. Expressed in egg-laying apparatus; hypodermis; pharynx; rectal muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and pancreatic cancer. Is an ortholog of human SNW1 (SNW domain containing 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1793Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16696)
DOID:3459Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16696)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16696)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16696)
Molecular_infoCorresponding_CDST27F2.1
Corresponding_transcriptT27F2.1.1
Other_sequence (44)
Associated_featureWBsf661754
WBsf232533
WBsf232534
WBsf232535
Experimental_infoRNAi_result (22)
Expr_patternExpr1923
Expr1924
Expr1025947
Expr1032385
Expr1157880
Expr2015833
Expr2034066
Drives_constructWBCnstr00010522
WBCnstr00035376
Construct_productWBCnstr00035376
Microarray_results (21)
Expression_clusterWBPaper00028451:Low_abundance_spermatogenesis_enriched
WBPaper00031040:TGF-beta_adult_downregulated
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00042477:RSR-2_complex
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045396:CACN-1_associated
WBPaper00045420:fertilization_upregulated_protein
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00046161:Q40-aggregate-protein_Day4_Sarcosyl-soluble
WBPaper00048910:mRNA-interacting_protein
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:body-wall-muscle_nucleus_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_nucleus_expressed
WBPaper00051245:nucleus_specific
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00055648:germline_expressed
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056034:pals-22(jy3)_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056826:SGP_biased
WBPaper00058691:WDR-5.1_interacting_protein
WBPaper00059334:SACY-1_interacting
WBPaper00059664:srbc-48(ac23)_downregulated
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061007:S.aquatilis_downregulated
WBPaper00061340:M1_parent
WBPaper00061340:Parent_of_exc_gland_AVK
WBPaper00061527:lst-3_9016-W03F9.10_13548
WBPaper00061527:R07E4.5-skp-1_1608
WBPaper00062056:lin-36(we36)_upregulated
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062293:isp-1(qm150)_upregulated
WBPaper00062498:PPM-1.D_interacting
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064716:paraquat_upregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065149:lin-52(n771)_upregulated
WBPaper00065373:sek-1(km4)_upregulated_cisplatin
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4386_cluster_6_1
cgc4489_group_4
WBPaper00025032:cluster_58
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00032165:differentially_expressed_with_age_medoid_1
WBPaper00035905:FBF-1_Associated
WBPaper00036286:Pattern_B
WBPaper00036375:depleted_in_PVD_OLL
WBPaper00041002:HF_3d_2.0mM_Down
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045263:ProLongevity-mtROS_upregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
[cgc5767]:expression_class_E
[cgc5767]:expression_class_ET
[cgc5767]:expression_class_ET_max(53_min)
[cgc5767]:expression_class_E_pi(53_min)
[cgc5767]:expression_class_E_pi(66_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
[cgc5767]:expression_class_MET
[cgc6390]:Cluster_F
[cgc6390]:oogenesis-enriched
Interaction (193)
Map_infoMapVPosition3.232Error0.001092
PositivePositive_cloneT27F2Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (18)
RemarkGene name created based on Pubmed 12084813 [krb 020719]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene