WormBase Tree Display for Gene: WBGene00004749
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| WBGene00004749 | SMap | S_parent | Sequence | F57C7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | sdn-1 | Person_evidence | WBPerson1831 | |||||
| Sequence_name | F57C7.3 | ||||||||
| Molecular_name | F57C7.3a | ||||||||
| F57C7.3a.1 | |||||||||
| CE05996 | |||||||||
| F57C7.3b | |||||||||
| CE32681 | |||||||||
| F57C7.3b.1 | |||||||||
| Other_name | CELE_F57C7.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | sdn-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sdn | ||||||||
| Allele (60) | |||||||||
| Strain | WBStrain00031428 | ||||||||
| WBStrain00000144 | |||||||||
| WBStrain00050774 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (42) | |||||||||
| Structured_description | Concise_description | sdn-1 encodes a homolog of vertebrate syndecan-2, a type I transmembrane heparan sulfate proteoglycan; by homology, SDN-1 is predicted to play a role in cell-cell and cell-matrix adhesion; loss of sdn-1 activity via RNA-mediated interference (RNAi) indicates that SDN-1 is required for backward locomotion and for normal development of the egg-laying system, particularly gonadal and vulval structures; SDN-1 is expressed in a subset of neuronal cell bodies and their associated processes in the nerve ring, and also in select tail neurons. | Paper_evidence | WBPaper00011289 | |||||
| WBPaper00018603 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Involved in embryo development; epidermis morphogenesis; and nematode larval development. Located in cell surface. Expressed in several structures, including neuroblasts; neurons; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Hodgkin's lymphoma; cleft lip; and glucose metabolism disease (multiple). Is an ortholog of human SDC1 (syndecan 1); SDC2 (syndecan 2); and SDC4 (syndecan 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||||
| DOID:8567 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||||
| DOID:4195 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10658) | ||||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||||||
| DOID:5844 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10661) | ||||||
| DOID:674 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10659) | ||||||
| Molecular_info | Corresponding_CDS | F57C7.3a | |||||||
| F57C7.3b | |||||||||
| Corresponding_CDS_history | F57C7.3:wp83 | ||||||||
| Corresponding_transcript | F57C7.3a.1 | ||||||||
| F57C7.3b.1 | |||||||||
| Other_sequence (22) | |||||||||
| Associated_feature (27) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00109528 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00109334 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048861 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00102205 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109237 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065732 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033032 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109625 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109431 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00000700 | ||||||||
| WBCnstr00001405 | |||||||||
| WBCnstr00001406 | |||||||||
| WBCnstr00019775 | |||||||||
| WBCnstr00020032 | |||||||||
| WBCnstr00035413 | |||||||||
| Construct_product (13) | |||||||||
| Antibody | WBAntibody00000804 | ||||||||
| WBAntibody00002534 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (124) | |||||||||
| Interaction (34) | |||||||||
| Anatomy_function | WBbtf0790 | ||||||||
| WBbtf0791 | |||||||||
| WBbtf0792 | |||||||||
| Map_info | Map | X | Position | 2.31221 | Error | 0.009839 | |||
| Positive | Positive_clone | F57C7 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4532 | |||||||
| 4652 | |||||||||
| 4134 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (47) | |||||||||
| Remark | Sequence connection from [Turnbull J, Kinnunen T]. krb 13/11/01 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
