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WormBase Tree Display for Gene: WBGene00004701

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Name Class

WBGene00004701SMapS_parentSequenceEEED8
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classrsp
Allele (22)
StrainWBStrain00047545
RNASeq_FPKM (74)
GO_annotation (16)
Contained_in_operonCEOP2743
Ortholog (36)
ParalogWBGene00004315Caenorhabditis elegansFrom_analysisPanther
WBGene00004703Caenorhabditis elegansFrom_analysisPanther
WBGene00013293Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionrsp-4 encodes, along with rsp-5, one of two C. elegans orthologs of the vertebrate SC35 splicing factor and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation.Paper_evidenceWBPaper00003988
Curator_confirmedWBPerson1843
Date_last_updated20 Mar 2012 00:00:00
Automated_descriptionPredicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and lung cancer (multiple). Is an ortholog of human SRSF2 (serine and arginine rich splicing factor 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:4467Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
DOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
DOID:6000Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
DOID:0050908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
DOID:3910Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
DOID:5410Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
DOID:3907Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
DOID:9119Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10783)
Molecular_infoCorresponding_CDSEEED8.7a
EEED8.7b
Corresponding_transcriptEEED8.7a.1
EEED8.7b.1
EEED8.7b.2
Other_sequence (52)
Associated_featureWBsf987876
WBsf1012225
WBsf223040
WBsf223041
WBsf223042
Experimental_infoRNAi_result (30)
Expr_patternExpr1140
Expr1022567
Expr1032321
Expr1147687
Expr2015561
Expr2033796
Drives_constructWBCnstr00010102
WBCnstr00035432
Construct_productWBCnstr00035432
Microarray_results (30)
Expression_cluster (132)
Interaction (117)
Map_infoMapIIPosition-1.7847Error0.000271
PositivePositive_cloneEEED8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4588
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene