WormBase Tree Display for Gene: WBGene00004701

WBGene00004701 SMap: S_parent: Sequence: EEED8
  Identity: Version: 1
    Name: CGC_name: rsp-4 Person_evidence: WBPerson297
      Sequence_name: EEED8.7
      Molecular_name: EEED8.7a
        EEED8.7a.1
        CE01891
        EEED8.7b
        CE27910
        EEED8.7b.1
        EEED8.7b.2
      Other_name: srp-2
        CeSC35
        CELE_EEED8.7 Accession_evidence: NDB BX284602
      Public_name: rsp-4
    DB_info: Database: AceView gene 2F678
        WormQTL gene WBGene00004701
        WormFlux gene WBGene00004701
        NDB locus_tag CELE_EEED8.7
        Panther gene CAEEL|WormBase=WBGene00004701|UniProtKB=Q09511
          family PTHR23147
        NCBI gene 173915
        RefSeq protein NM_001393068.1
            NM_062613.4
        SwissProt UniProtAcc Q09511
        TREEFAM TREEFAM_ID TF106262
        UniProt_GCRP UniProtAcc Q09511
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rsp
    Allele (22)
    Strain: WBStrain00047545
    RNASeq_FPKM (74)
    GO_annotation (16)
    Contained_in_operon: CEOP2743
    Ortholog: WBGene00057380 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00025445 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00164891 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00156613 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00131429 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00107713 Pristionchus pacificus From_analysis: OMA
      WBGene00223375 Brugia malayi From_analysis: WormBase-Compara
      CSP21.g1817 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g9061 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g16936 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g9735 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g27189 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g3640 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g14342 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g16588 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g16608 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g6382 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g7166 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00131.g5185 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-rsp-4 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g11456 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00082.g3684 Caenorhabditis sinica From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02381 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g18433 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20101700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g4481 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00207844 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00264657 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00287046 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0265298 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-2420 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040426-2706 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      HGNC:10783 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            PhylomeDB
            SonicParanoid
      HGNC:16988 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            PhylomeDB
            SonicParanoid
      MGI:98284 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            PhylomeDB
            SonicParanoid
      RGD:1359422 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00004315 Caenorhabditis elegans From_analysis: Panther
      WBGene00004703 Caenorhabditis elegans From_analysis: Panther
      WBGene00013293 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: rsp-4 encodes, along with rsp-5, one of two C. elegans orthologs of the vertebrate SC35 splicing factor and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation. Paper_evidence: WBPaper00003988
          Curator_confirmed: WBPerson1843
          Date_last_updated: 20 Mar 2012 00:00:00
      Automated_description: Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and lung cancer (multiple). Is an ortholog of human SRSF2 (serine and arginine rich splicing factor 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:4467 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
      DOID:3908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
      DOID:6000 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
      DOID:0050908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
      DOID:3910 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
      DOID:5410 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
      DOID:3907 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
      DOID:9119 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10783)
  Molecular_info: Corresponding_CDS: EEED8.7a
      EEED8.7b
    Corresponding_transcript: EEED8.7a.1
      EEED8.7b.1
      EEED8.7b.2
    Other_sequence (52)
    Associated_feature: WBsf987876
      WBsf1012225
      WBsf223040
      WBsf223041
      WBsf223042
  Experimental_info: RNAi_result (30)
    Expr_pattern: Expr1140
      Expr1022567
      Expr1032321
      Expr1147687
      Expr2015561
      Expr2033796
    Drives_construct: WBCnstr00010102
      WBCnstr00035432
    Construct_product: WBCnstr00035432
    Microarray_results (30)
    Expression_cluster (132)
    Interaction (117)
  Map_info: Map: II Position: -1.7847 Error: 0.000271
    Positive: Positive_clone: EEED8 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4588
    Pseudo_map_position
  Reference (14)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene