WormBase Tree Display for Gene: WBGene00004510
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| WBGene00004510 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | rrf-3 | Person_evidence | WBPerson398 | |||||
| Sequence_name | F10B5.7 | ||||||||
| Molecular_name | F10B5.7 | ||||||||
| F10B5.7.1 | |||||||||
| CE45624 | |||||||||
| Other_name | fer-15 | Person_evidence | WBPerson680 | ||||||
| CELE_F10B5.7 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | rrf-3 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 06 Jun 2016 10:55:30 | WBPerson2970 | Event | Acquires_merge | WBGene00001421 | ||||
| Name_change | Other_name | fer-15 | |||||||
| Acquires_merge | WBGene00001421 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rrf | ||||||||
| Reference_allele | WBVar00087749 | ||||||||
| Allele (86) | |||||||||
| Legacy_information | hc15ts : hermaphrodites and males grown at 25x produce spermatids that fail to activate into spermatozoa. Self-fertility < 1% (25x) 100% (16x). ES2 (adult). Similar phenotype in hc15/Df. NA3 (hc89 b26). | ||||||||
| [C.elegansII] hc15ts : hermaphrodites and males grown at 25C produce spermatids that fail to activate into spermatozoa. Self-fertility < 1% (25C) 100% (16C). ES2 (adult). Similar phenotype in hc15/Df. OA2: hc89, b26. See also age-1. [Roberts and Ward 1982; BA; TJ; SL] | |||||||||
| Strain (39) | |||||||||
| In_cluster | conserved_miRNA_siRNA_cluster | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (31) | |||||||||
| Paralog | WBGene00001214 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00004508 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00004509 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | rrf-3 encodes an RNA-directed RNA polymerase (RdRP) homolog that inhibits somatic RNAi, and thus promotes activity of repeated genes (e.g., multicopy transgenic arrays); the effect of RRF-3 on RNAi is opposite to that of RRF-1 (which stimulates somatic RNAi), which might arise from competition by RRF-3 with RRF-1 or EGO-1 in RNAi formation; rrf-3 mutants are hypersensitive to somatic RNAi, and conversely suppress the activity of an integrated rol6 (su1006) transgene. | Paper_evidence | WBPaper00004137 | |||||
| WBPaper00005423 | |||||||||
| WBPaper00006395 | |||||||||
| WBPaper00013304 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA-dependent RNA polymerase activity. Involved in regulatory ncRNA-mediated heterochromatin formation and spermatogenesis. Predicted to be part of nuclear RNA-directed RNA polymerase complex. Expressed in head and tail. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F10B5.7 | |||||||
| Corresponding_CDS_history | F10B5.7:wp222 | ||||||||
| Corresponding_transcript | F10B5.7.1 | ||||||||
| Other_sequence | Acan_isotig16813 | ||||||||
| CBC02376_1 | |||||||||
| AE03845 | |||||||||
| JI164335.1 | |||||||||
| AYC02866_1 | |||||||||
| Tcir_isotig07024 | |||||||||
| JI471910.1 | |||||||||
| HQ611979.1 | |||||||||
| Associated_feature | WBsf644446 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00000533 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00044213 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram279 | ||||||||
| Expr5712 | |||||||||
| Expr1017743 | |||||||||
| Expr1032312 | |||||||||
| Expr1148172 | |||||||||
| Expr2015545 | |||||||||
| Expr2033780 | |||||||||
| Drives_construct | WBCnstr00002564 | ||||||||
| WBCnstr00035434 | |||||||||
| Construct_product | WBCnstr00035434 | ||||||||
| Regulate_expr_cluster (15) | |||||||||
| Antibody | WBAntibody00002898 | ||||||||
| WBAntibody00002903 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (106) | |||||||||
| Interaction (149) | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| WBbiopr:00000057 | |||||||||
| Map_info | Map | II | Position | 0.738281 | Error | 0.001232 | |||
| Positive | Positive_clone | F10B5 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4646 | |||||||
| 4965 | |||||||||
| 838 | |||||||||
| 839 | |||||||||
| 1063 | |||||||||
| 1068 | |||||||||
| 1072 | |||||||||
| Pos_neg_data (38) | |||||||||
| Pseudo_map_position | |||||||||
| Reference (259) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
