WormBase Tree Display for Gene: WBGene00004507
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| WBGene00004507 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C18H9 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | rpy-1 | Person_evidence | WBPerson360 | |||||
| Sequence_name | C18H9.7 | ||||||||
| Molecular_name | C18H9.7 | ||||||||
| C18H9.7.1 | |||||||||
| CE51338 | |||||||||
| C18H9.7.2 | |||||||||
| Other_name | rap-1 | Person_evidence | WBPerson451 | ||||||
| WBPerson360 | |||||||||
| CELE_C18H9.7 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | rpy-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rpy | ||||||||
| Allele (56) | |||||||||
| Legacy_information | [Nonet ML] rap for RAPsyn family. Predicted gene C18H9.7 | ||||||||
| [C.elegansII] NMK. Encodes ras-related protein. [MH] | |||||||||
| Strain | WBStrain00001487 | ||||||||
| WBStrain00001386 | |||||||||
| WBStrain00029059 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00000092 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WormBase-Compara | |||||||||
| WBGene00021247 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | rpy-1 is orthologous to the human gene 43KDA ACETYLCHOLINE RECEPTOR-ASSOCIATED PROTEIN (RAPSN; OMIM:601592), which when mutated leads to congenital myasthenic syndrome. | Curator_confirmed | WBPerson1823 | |||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable acetylcholine receptor binding activity. Predicted to be involved in cholinergic synaptic transmission and positive regulation of neuromuscular synaptic transmission. Predicted to be located in neuromuscular junction and plasma membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 11 and fetal akinesia deformation sequence syndrome 2. Is an ortholog of human RAPSN (receptor associated protein of the synapse). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111378 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9863) | ||||
| DOID:0110675 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9863) | ||||||
| Molecular_info | Corresponding_CDS | C18H9.7 | |||||||
| Corresponding_CDS_history | C18H9.7:wp252 | ||||||||
| Corresponding_transcript | C18H9.7.1 | ||||||||
| C18H9.7.2 | |||||||||
| Other_sequence | JI168699.1 | ||||||||
| OOC01460_1 | |||||||||
| MJC01218_1 | |||||||||
| Acan_isotig22916 | |||||||||
| Oden_isotig20580 | |||||||||
| MJ00259 | |||||||||
| MIC05093_1 | |||||||||
| JI480958.1 | |||||||||
| Dviv_isotig35264 | |||||||||
| BUC00303_1 | |||||||||
| Associated_feature | WBsf717691 | ||||||||
| WBsf988231 | |||||||||
| WBsf988232 | |||||||||
| WBsf1012413 | |||||||||
| WBsf1012414 | |||||||||
| WBsf223224 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00113498 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00094738 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011043 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040996 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00084235 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029104 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076154 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023059 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00117640 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00002277 | ||||||||
| WBCnstr00004285 | |||||||||
| WBCnstr00012279 | |||||||||
| WBCnstr00013178 | |||||||||
| WBCnstr00017032 | |||||||||
| WBCnstr00035436 | |||||||||
| Construct_product | WBCnstr00035436 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (171) | |||||||||
| Interaction (93) | |||||||||
| Map_info | Map | II | Position | -0.027018 | Error | 0.008772 | |||
| Positive | Positive_clone | C18H9 | Person_evidence | WBPerson451 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4643 | |||||||
| Pseudo_map_position | |||||||||
| Reference (27) | |||||||||
| Remark | [Han M] ras-related protein. Very similar to mammalian rap1A (Krev). | ||||||||
| This other_name rap-1 is not the same as the CGC main name rap-1 (C27B7.8) | CGC_data_submission | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
