rpn-11 encodes a predicted non-ATPase subunit of the 19S regulatory complex of the proteasome that affects adult viability, osmoregulation, embryonic viability, and movement; interacts with itself, RPN-9, and F55A11.3, based on yeast two-hybrid assays.
Predicted to enable metallopeptidase activity and proteasome binding activity. Involved in programmed cell death involved in cell development. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is an ortholog of human PSMD14 (proteasome 26S subunit, non-ATPase 14).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.