WormBase Tree Display for Gene: WBGene00001231

WBGene00001231 Evidence: Person_evidence: WBPerson599
  SMap: S_parent: Sequence: C41D11
  Identity: Version: 1
    Name: CGC_name: eif-3.H
      Sequence_name: C41D11.2
      Molecular_name: C41D11.2
        C41D11.2.1
        CE29220
      Other_name: CELE_C41D11.2 Accession_evidence: NDB BX284601
      Public_name: eif-3.H
    DB_info: Database: AceView gene 1F13
        WormQTL gene WBGene00001231
        WormFlux gene WBGene00001231
        NDB locus_tag CELE_C41D11.2
        Panther gene CAEEL|WormBase=WBGene00001231|UniProtKB=O01974
          family PTHR10410
        NCBI gene 172044
        RefSeq protein NM_058969.5
        SwissProt UniProtAcc O01974
        TREEFAM TREEFAM_ID TF101504
        UniProt_GCRP UniProtAcc O01974
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:23 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: eif
    Allele (35)
    Strain: WBStrain00001189
      WBStrain00001416
      WBStrain00001542
      WBStrain00001543
      WBStrain00036124
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (36)
    Paralog: WBGene00000817 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00004467 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018135 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable metallopeptidase activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in formation of cytoplasmic translation initiation complex. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic 43S preinitiation complex; eukaryotic translation initiation factor 3 complex; and polysomal ribosome. Human ortholog(s) of this gene implicated in breast cancer and prostate carcinoma. Is an ortholog of human EIF3H (eukaryotic translation initiation factor 3 subunit H). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10286 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3273)
      DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3273)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3273)
  Molecular_info: Corresponding_CDS: C41D11.2
    Corresponding_transcript: C41D11.2.1
    Other_sequence (51)
    Associated_feature: WBsf643216
      WBsf643217
      WBsf217531
      WBsf217532
  Experimental_info: RNAi_result: WBRNAi00024792 Inferred_automatically: RNAi_primary
      WBRNAi00003124 Inferred_automatically: RNAi_primary
      WBRNAi00114605 Inferred_automatically: RNAi_primary
      WBRNAi00042285 Inferred_automatically: RNAi_primary
      WBRNAi00070968 Inferred_automatically: RNAi_primary
      WBRNAi00111908 Inferred_automatically: RNAi_primary
      WBRNAi00024791 Inferred_automatically: RNAi_primary
      WBRNAi00066086 Inferred_automatically: RNAi_primary
      WBRNAi00116711 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram178
      Chronogram1397
      Chronogram1990
      Expr5481
      Expr5482
      Expr1021959
      Expr1030779
      Expr1146276
      Expr2011258
      Expr2029494
    Drives_construct: WBCnstr00002081
      WBCnstr00004215
    Microarray_results (19)
    Expression_cluster (141)
    Interaction (137)
  Map_info: Map: I Position: -1.30523 Error: 0.000936
    Positive: Positive_clone: C41D11 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5247
    Pseudo_map_position
  Reference: WBPaper00027281
    WBPaper00028984
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00064339
  Remark: The capital letters are used here to distinguish the different eIF3 subunit genes. This roughly agrees with worm gene nomenclature and it makes clear the orthologies for these universal factors (eif-3B corresponding to eIF3b, and so on), in the unified eIF3 nomenclature proposed by Browning KS et al (2001)[JAH][030106 ck1]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene