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WormBase Tree Display for Gene: WBGene00004419

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Name Class

WBGene00004419SMapS_parentSequenceY24D9A
IdentityVersion3
NameCGC_namerpl-7A
Sequence_nameY24D9A.4
Molecular_nameY24D9A.4
Y24D9A.4.1
CE27398
Other_namerpl-8CGC_data_submission
phi-22Person_evidenceWBPerson2582
Surf-3Paper_evidenceWBPaper00013574
CELE_Y24D9A.4Accession_evidenceNDBBX284604
Public_namerpl-7A
DB_infoDatabaseAceViewgene4F154
WormQTLgeneWBGene00004419
WormFluxgeneWBGene00004419
NDBlocus_tagCELE_Y24D9A.4
PanthergeneCAEEL|WormBase=WBGene00004419|UniProtKB=Q966C6
familyPTHR23105
NCBIgene177203
RefSeqproteinNM_171316.9
SwissProtUniProtAccQ966C6
UniProt_GCRPUniProtAccQ966C6
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
206 Jul 2004 10:07:57WBPerson1971Name_changeCGC_namerpl-7A
317 Mar 2005 13:55:29WBPerson2970Name_changeOther_namephi-22
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrpl
Allele (32)
Legacy_informationOrthologous to yeast (S.cerevisiae) ribosomal protein rpl8 using blastP
StrainWBStrain00003400
RNASeq_FPKM (74)
GO_annotation00090857
00090858
00090859
00090860
00090861
00090862
00090863
Ortholog (53)
ParalogWBGene00004412Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010896Caenorhabditis elegansFrom_analysisPanther
WBGene00012964Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00009993Caenorhabditis elegansFrom_analysisPanther
WBGene00017997Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionrpl-7A encodes a large ribosomal subunit L7a protein required in mass RNAi assays for fertility, vulval development, and general health; the rpl-7A transcription unit has one nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-7A is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-10, rpl-12) have protein products that are involved in translation; RPL-7A binds bovine calmodulin in vitro in a calcium-dependent manner.Paper_evidenceWBPaper00004313
WBPaper00005654
WBPaper00006395
WBPaper00031011
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated04 May 2010 00:00:00
Automated_descriptionEnables calmodulin binding activity. Predicted to be involved in maturation of LSU-rRNA. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL7A (ribosomal protein L7a).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY24D9A.4
Corresponding_CDS_historyY24D9A.4b:wp121
Y24D9A.4c:wp270
Corresponding_transcriptY24D9A.4.1
Corresponding_transcript_historyY24D9A.4d:wp195
Other_sequence (195)
Associated_featureWBsf651726
WBsf667668
WBsf667875
WBsf981739
WBsf229958
Experimental_infoRNAi_result (13)
Expr_patternChronogram355
Expr6909
Expr1020085
Expr1032223
Expr1159240
Expr2015481
Expr2033716
Drives_constructWBCnstr00003868
Microarray_results (30)
Expression_cluster (184)
Interaction (312)
Map_infoMapIVPosition0.197591Error0.00512
PositivePositive_cloneY24D9AInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00013574
WBPaper00028807
WBPaper00031011
WBPaper00038491
WBPaper00049828
WBPaper00055090
WBPaper00060662
WBPaper00062737
WBPaper00064158
WBPaper00065861
RemarkThis gene previously was known as rpl-8 with rpl-7A as an other name. Following advice from the CGC, this situation has been reversed and rpl-7A is now the main (CGC approved) name for this gene [040706 krb]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene