WormBase Tree Display for Gene: WBGene00004414
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| WBGene00004414 | SMap | S_parent | Sequence | CHROMOSOME_III | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rpl-3 | |||||||
| Sequence_name | F13B10.2 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | CELE_F13B10.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | rpl-3 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rpl | ||||||||
| Allele (27) | |||||||||
| Legacy_information | Orthologous to yeast (S.cerevisiae) ribosomal protein rpl3 using blastP | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (45) | |||||||||
| Structured_description | Concise_description | rpl-3 encodes a large ribosomal subunit L3 protein required in mass RNAi assays for embryonic and larval viability, fertility, and general health; the rpl-3 transcription unit has a nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-3 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-7, rpl-10, rpl-12) have protein products that are involved in translation. | Paper_evidence | WBPaper00004313 | |||||
| WBPaper00004403 | |||||||||
| WBPaper00004651 | |||||||||
| WBPaper00005654 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2D. Is an ortholog of human RPL3 (ribosomal protein L3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0081160 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10351) | ||||
| Molecular_info | Corresponding_CDS | F13B10.2a | |||||||
| F13B10.2c | |||||||||
| F13B10.2d | |||||||||
| Corresponding_transcript | F13B10.2b | ||||||||
| F13B10.2a.1 | |||||||||
| F13B10.2a.2 | |||||||||
| F13B10.2c.1 | |||||||||
| F13B10.2d.1 | |||||||||
| Other_sequence (421) | |||||||||
| Associated_feature (15) | |||||||||
| Experimental_info | RNAi_result (22) | ||||||||
| Expr_pattern | Expr1021197 | ||||||||
| Expr1032218 | |||||||||
| Expr1148423 | |||||||||
| Expr2015473 | |||||||||
| Expr2033708 | |||||||||
| Drives_construct | WBCnstr00035504 | ||||||||
| Construct_product | WBCnstr00035504 | ||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (177) | |||||||||
| Interaction (375) | |||||||||
| Map_info | Map | III | Position | -4.2473 | Error | 0.000149 | |||
| Positive | Positive_clone | F13B10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
