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WormBase Tree Display for Gene: WBGene00004414

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Name Class

WBGene00004414SMapS_parentSequenceCHROMOSOME_III
IdentityVersion1
NameCGC_namerpl-3
Sequence_nameF13B10.2
Molecular_name (11)
Other_nameCELE_F13B10.2Accession_evidenceNDBBX284603
Public_namerpl-3
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrpl
Allele (27)
Legacy_informationOrthologous to yeast (S.cerevisiae) ribosomal protein rpl3 using blastP
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (45)
Structured_descriptionConcise_descriptionrpl-3 encodes a large ribosomal subunit L3 protein required in mass RNAi assays for embryonic and larval viability, fertility, and general health; the rpl-3 transcription unit has a nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-3 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-7, rpl-10, rpl-12) have protein products that are involved in translation.Paper_evidenceWBPaper00004313
WBPaper00004403
WBPaper00004651
WBPaper00005654
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2D. Is an ortholog of human RPL3 (ribosomal protein L3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0081160Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10351)
Molecular_infoCorresponding_CDSF13B10.2a
F13B10.2c
F13B10.2d
Corresponding_transcriptF13B10.2b
F13B10.2a.1
F13B10.2a.2
F13B10.2c.1
F13B10.2d.1
Other_sequence (421)
Associated_feature (15)
Experimental_infoRNAi_result (22)
Expr_patternExpr1021197
Expr1032218
Expr1148423
Expr2015473
Expr2033708
Drives_constructWBCnstr00035504
Construct_productWBCnstr00035504
Microarray_resultsSMD_F13B10.2
SMD_F13B10.2:2
191663_at
A_12_P102842
A_12_P156935
Aff_F13B10.2
GPL13394_WBGene00004414
GPL13914_F13B10.2
GPL14144_F13B10.2a_1129-1188_0.959_1_A
GPL14144_F13B10.2a_685-744_0.904_8_C
GPL14144_F13B10.2a_811-870_0.935_2_B
GPL19516_CGZ0015809
GPL19516_CGZ0015810
GPL19516_CGZ0015811
GPL19516_CGZ0015812
GPL19516_CGZ0015813
GPL19516_CGZ0015814
GPL21109_F13B10.2a.1
GPL21109_F13B10.2a.2
GPL3518_CE05598
GPL8304_CE_WBGene00004414_A
GPL8304_CE_WBGene00004414_B
GPL8673_F13B10_2aP00029
GPL8673_F13B10_2aP00133
GPL8673_F13B10_2aP00695
GPL8673_F13B10_2cP00029
GPL8673_F13B10_2cP00133
GPL8673_F13B10_2cP00551
GPL8673_F13B10_2dP00029
GPL8673_F13B10_2dP00404
GPL8673_F13B10_2dP00635
GPL9450_F13B10.2
cea2.c.18707
Expression_cluster (177)
Interaction (375)
Map_infoMapIIIPosition-4.2473Error0.000149
PositivePositive_cloneF13B10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene