WormBase Tree Display for Gene: WBGene00004332

WBGene00004332 SMap: S_parent: Sequence: Y18H1A
  Identity: Version: 2
    Name: CGC_name: rec-1 Person_evidence: WBPerson533
            WBPerson1795
      Sequence_name: Y18H1A.7
      Molecular_name: Y18H1A.7a
        Y18H1A.7a.1
        CE33587
        Y18H1A.7b
        CE49243
        Y18H1A.7b.1
      Other_name: CELE_Y18H1A.7 Accession_evidence: NDB BX284601
      Public_name: rec-1
    DB_info: Database: NDB locus_tag CELE_Y18H1A.7
        NCBI gene 171664
        RefSeq protein NM_058372.8
            NM_001306247.3
        TrEMBL UniProtAcc V6CLD8
            Q9BL91
        UniProt_GCRP UniProtAcc Q9BL91
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 13 Oct 2015 08:38:50 WBPerson2970 Event: Acquires_merge: WBGene00021211
              Name_change: Sequence_name: Y18H1A.7
      Acquires_merge: WBGene00021211
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rec
    Reference_allele: WBVar00241753
    Allele (41)
    Legacy_information: s180 : general enhancer of meiotic recombination. ES1.
      Increase recomb.
      See also s180
      [Rose AM ] increases meiotic recombination in gene clusters, reduces recombination on chromosome arms, distribution of crossovers in Rec-1 approximates physical map. ES1 ME3 NA1.
      [C.elegansII] s180 : increases meiotic recombination in gene clusters, reduces recombination on chromosome arms; distribution of crossovers in Rec-1 approximates physical map. ES1, ME3. NA1. [Rose and Baillie 1979; Zetka and Rose 1995; KR]
    Strain (22)
    RNASeq_FPKM (74)
    GO_annotation: 00091998
      00091999
      00092000
    Ortholog: chrI_pilon.g113 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: rec-1 affects the recombination frequency in the central gene cluster region of autosomes and has been shown to alter the distribution of genes on the genetic map of the X chromosome, also affects X-chromosome nondisjunction; does not appear to act pre-meiotically. Paper_evidence: WBPaper00001046
            WBPaper00002339
            WBPaper00017219
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 29 Sep 2015 00:00:00
      Automated_description: Involved in meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y18H1A.7a
      Y18H1A.7b
    Corresponding_CDS_history: Y18H1A.7:wp96
    Corresponding_transcript: Y18H1A.7a.1
      Y18H1A.7b.1
    Associated_feature: WBsf648913
      WBsf982561
      WBsf1009119
      WBsf218932
  Experimental_info: RNAi_result: WBRNAi00055631 Inferred_automatically: RNAi_primary
      WBRNAi00084348 Inferred_automatically: RNAi_primary
      WBRNAi00103863 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028467
      Expr1039252
      Expr1159145
      Expr2015290
      Expr2033524
    Drives_construct: WBCnstr00020890
      WBCnstr00020891
      WBCnstr00020892
    Construct_product: WBCnstr00020890
      WBCnstr00020892
    Microarray_results (14)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037946:LIN-39_interacting
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00041506:P1_enriched
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00046012:tdp-1(ok803)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:sod-2(ok1030)_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Metformin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00060951:mrpl-2(osa3)_upregulated
      WBPaper00061203:let-418(n3536)_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061340:g2
      WBPaper00061340:Germline
      WBPaper00061340:Parent_of_hyp3_ILsoDx
      WBPaper00061340:Parent_of_K_Kprime
      WBPaper00062056:dpl-1(n2994)_downregulated
      WBPaper00062056:lin-35(n745)_downregulated
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064716:paraquat_upregulated
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_1
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00044013:nasp-1_downregulated
      [cgc6390]:Cluster_F
      [cgc6390]:intrinsic
    WBProcess: WBbiopr:00000109
  Map_info: Map: I Position: -18.5556
    Well_ordered
    Positive: Inside_rearr: eDf24
      Positive_clone: Y18H1A Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Pos_neg_data: 8939
        8940
        8941
        8942
        8943
  Reference (28)
  Method: Gene